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Metaboost Rx vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Metaboost Rx logo

Metaboost Rx

6.5
★★★☆☆3.3/5

Best for: flat-rate semaglutide/tirzepatide plus a lower-dose microdose track for side-effect-sensitive patients

Visit Metaboost Rx
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Metaboost Rx and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Metaboost Rx

Standing monthly rate, injectionCompounded
$249/mo
semaglutide

Flat rate; 'no dose-change surcharges' per program FAQ

Standing monthly rate, injectionCompounded
$299/mo
tirzepatide

Flat rate; 'no dose-change surcharges' per program FAQ

GLP-1 Microdose — lower-dose protocol, body-composition/metabolic focus (not primary weight loss)Compounded
$199/mo
semaglutide

Positioned as an alternative to the standard Semaglutide program, not a starter tier of it

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Metaboost Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Metaboost Rx

6.5/10

Overall

Amazon One Medical

8.5/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

4.5A
vs
B
8.8

Accessibility10%

6.0A
vs
B
9.5

Support10%

6.5A
vs
B
8.0

Features & Coverage

FeatureMetaboost RxAmazon One Medical
Starting Price$199/mo$149/mo
Features7 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Metaboost Rx

Metaboost Rx is an Oklahoma City-based telehealth practice offering physician-directed compounded GLP-1 programs. Semaglutide runs a flat $249/mo and tirzepatide $299/mo, plus a lower-dose GLP-1 Microdose track from $199/mo — each billed monthly with a 'no dose-change surcharges' promise. Eligibility is checked before payment; a separate peptide-therapy track is also offered.

Read our full Metaboost Rx review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Metaboost Rx

What we like

  • Named legal entity (Metaboost-Rx LLC) with real Terms, Privacy, and HIPAA Notice pages, not just boilerplate
  • Flat per-program pricing with a 'no dose-change surcharges' promise — sema $249/mo, tirz $299/mo, microdose $199/mo
  • Pay-after-approval funnel: eligibility check comes before payment, and Terms confirm a refund if a provider declines
  • Adds a distinct lower-dose GLP-1 Microdose track for patients who want metabolic benefits without aggressive weight loss

Watch-outs

  • Trustpilot 'Rated Excellent 4.8/5' and '300+ Google reviews' badges have zero outbound links — can't be independently verified
  • A named customer's exact quote is reused as both a before/after photo caption and a separate 'Google review' — a templated-testimonial tell
  • State availability is inconsistent: one FAQ claims 'all 50 states,' another says only 'the states where we operate,' with no published list
  • Contact is a Gmail address (metaboostrx@gmail.com) and the listed address is a suite/mailbox-style unit, not a standalone clinic
  • Cancellation terms conflict — Terms of Service say cancel anytime, but every program FAQ requires 30 days' notice before the next billing cycle
  • No named compounding pharmacy partner and no LegitScript or PCAB accreditation shown anywhere on the site

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Metaboost Rx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Metaboost Rx remains a solid alternative, especially if you're looking for flat-rate semaglutide/tirzepatide plus a lower-dose microdose track for side-effect-sensitive patients.

Choose Metaboost Rx if…

You want flat-rate semaglutide/tirzepatide plus a lower-dose microdose track for side-effect-sensitive patients and a starting price around $199/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

7.5

PeterMD

Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy

7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

Metaboost Rx vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.