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Medsol RX vs Collective

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Medsol RX logo

Medsol RX

7.3
★★★3.7/5

Best for: flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach

Visit Medsol RX
VS
Collective logo

Collective

8.3
★★★★4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective

Medsol RX and Collective are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $209/mo, and Collective edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Medsol RX

Compounded SemaglutideCompounded
$209/mo
semaglutide

12-mo plan; $229 (6-mo), $249 (3-mo), or $199 first month then $279 month-to-month

Compounded TirzepatideCompounded
$250/mo
tirzepatide

From ~$250/mo compounded; varies by dose

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

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What’s included

Medsol RX

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Medsol RX

7.3/10

Overall

Collective

8.3/10

Value25%

7.0A
vs
B
9.4

Effectiveness25%

7.5A
vs
B
8.2

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
7.2

Accessibility10%

7.5A
vs
B
7.4

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureMedsol RXCollective
Starting Price$209/mo$59/mo
Features7 features3 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Medsol RX

Medsol RX is a GLP-1 weight-loss telehealth program offering compounded semaglutide (from $209/mo) and tirzepatide, prescribed by board-certified clinicians via OpenLoop and shipped nationwide. Plans bundle the medication with a dedicated care coach, custom treatment plan, and medical oversight; it's HSA/FSA eligible with Klarna financing and offers month-to-month or 3/6/12-month options, plus microdosing and wellness add-ons.

Read our full Medsol RX review →

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

Pros & Cons

Medsol RX

What we like

  • Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
  • Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
  • Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide
  • Month-to-month option ($199 first month) with no long-term commitment, plus microdosing and wellness add-ons

Watch-outs

  • Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
  • No legal entity name published on the site
  • Tirzepatide pricing is given as a range ($250-$1,400/mo), not a fixed rate
  • Compounded GLP-1s are not FDA-approved (the site discloses this)

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Our Verdict

Winner: Collective

Collective edges out Medsol RX with a higher overall score of 8.3/10 and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. Medsol RX remains a solid alternative, especially if you're looking for flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach.

Choose Medsol RX if…

You want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach and a starting price around $209/mo.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

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Broadest GLP-1 formulary including Foundayo on day-one of launch

8.0

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7.2

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Medsol RX vs Collective: FAQ

Collective is cheaper. Its lowest ongoing monthly cash price is $59/mo, compared with $209/mo for Medsol RX. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Collective scores higher overall at 8.3/10 versus 7.3/10, and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. That said, Medsol RX is a better fit if you want flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach.
Medsol RX lists availability in 50 states, while Collective's state list is not publicly listed.
Collective is an affiliate partner (we may earn a commission on sign-ups through our links); Medsol RX is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, Collective is cheaper at $59/mo versus $209/mo at Medsol RX.

Key terms, explained

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Continue exploring Medsol RX and Collective head-to-heads in the same category.

Or see the full category ranking.

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