MedLeanRx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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MedLeanRx
Best for: Texas-only compounded semaglutide at $149/mo, plus brand options
Visit MedLeanRx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →MedLeanRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $149/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MedLeanRx
Weekly semaglutide vial $149/mo; plans 'start at $149/month for the starting dose' — pricing may vary with medication and dosage
Needle-free daily oral semaglutide tablets, $149/mo
$269/mo standard; intro bundle: 2-month supply at 2 mg weekly for $325 (~$163/mo), Texas clients only, while supplies last
NewSelf
All dosages same price
All dosages same price
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What’s included
MedLeanRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MedLeanRx
7.2/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MedLeanRx | NewSelf |
|---|---|---|
| Starting Price | $149/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | 1 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MedLeanRx
MedLeanRx is a physician-guided telehealth weight-loss clinic serving Texas only, based in Spring, TX. It prescribes compounded semaglutide as a weekly injection or daily oral tablet at $149/month and compounded tirzepatide at $269/month, plus a brand pathway for Wegovy, Zepbound, and Foundayo (orforglipron) at a $99/month fee where medication is billed separately. A 5-minute online assessment gets a 24-48 hour physician review, with free shipping and cancel-anytime plans.
Read our full MedLeanRx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
MedLeanRx
What we like
- Compounded semaglutide $149/mo in both weekly injection and daily oral tablet form
- Brand pathway for Wegovy, Zepbound, and Foundayo (orforglipron) at a $99/mo fee plus medication cost
- Intro bundle: 2 months of compounded tirzepatide (2 mg weekly) for $325 — about $163/mo
- LegitScript seal displayed; named supervising physician (Dr. Johnson Uzor, MD)
- Free shipping, no hidden fees, and cancel-anytime plans per homepage trust chips
- 5-minute online assessment with 24-48 hour physician review — 100% online, no clinic visits
Watch-outs
- Texas only — not available in the other 49 states
- Compounded tirzepatide is $269/mo at standard pricing, above the ~$249 market median
- Strict no-refund policy: 'All sales are final' per Terms & Conditions
- Pharmacy partner not publicly named — a transparency gap for a compounding service
- Legal entity name and founding details not published on the site
- Brand-medication total cost not published — $99/mo fee plus the separate cost of medication
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out MedLeanRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. MedLeanRx remains a solid alternative, especially if you're looking for Texas-only compounded semaglutide at $149/mo, plus brand options.
Choose MedLeanRx if…
You want Texas-only compounded semaglutide at $149/mo, plus brand options and a starting price around $149/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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TMates
Nationwide compounded GLP-1 availability including Puerto Rico
From $249/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →MedLeanRx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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