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MedLeanRx vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
MedLeanRx logo

MedLeanRx

7.2
★★★3.6/5

Best for: Texas-only compounded semaglutide at $149/mo, plus brand options

Visit MedLeanRx
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

MedLeanRx and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, MedLeanRx starts lower at $149/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

MedLeanRx

StartingCompounded
$149/mo
semaglutide

Weekly semaglutide vial $149/mo; plans 'start at $149/month for the starting dose' — pricing may vary with medication and dosage

StartingCompounded · oral
$149/mo
semaglutide

Needle-free daily oral semaglutide tablets, $149/mo

StartingCompounded
$269$163/mo
Save 39% right now
tirzepatide

$269/mo standard; intro bundle: 2-month supply at 2 mg weekly for $325 (~$163/mo), Texas clients only, while supplies last

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

MedLeanRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

MedLeanRx

7.2/10

Overall

Vytora Health

8.4/10

Value25%

8.0A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
9.3

Accessibility10%

4.5A
vs
B
8.5

Support10%

7.0A
vs
B
8.4

Features & Coverage

FeatureMedLeanRxVytora Health
Starting Price$149/mo$150/mo
Features8 features8 features
States Available151
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About MedLeanRx

MedLeanRx is a physician-guided telehealth weight-loss clinic serving Texas only, based in Spring, TX. It prescribes compounded semaglutide as a weekly injection or daily oral tablet at $149/month and compounded tirzepatide at $269/month, plus a brand pathway for Wegovy, Zepbound, and Foundayo (orforglipron) at a $99/month fee where medication is billed separately. A 5-minute online assessment gets a 24-48 hour physician review, with free shipping and cancel-anytime plans.

Read our full MedLeanRx review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

MedLeanRx

What we like

  • Compounded semaglutide $149/mo in both weekly injection and daily oral tablet form
  • Brand pathway for Wegovy, Zepbound, and Foundayo (orforglipron) at a $99/mo fee plus medication cost
  • Intro bundle: 2 months of compounded tirzepatide (2 mg weekly) for $325 — about $163/mo
  • LegitScript seal displayed; named supervising physician (Dr. Johnson Uzor, MD)
  • Free shipping, no hidden fees, and cancel-anytime plans per homepage trust chips
  • 5-minute online assessment with 24-48 hour physician review — 100% online, no clinic visits

Watch-outs

  • Texas only — not available in the other 49 states
  • Compounded tirzepatide is $269/mo at standard pricing, above the ~$249 market median
  • Strict no-refund policy: 'All sales are final' per Terms & Conditions
  • Pharmacy partner not publicly named — a transparency gap for a compounding service
  • Legal entity name and founding details not published on the site
  • Brand-medication total cost not published — $99/mo fee plus the separate cost of medication

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out MedLeanRx with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. MedLeanRx remains a solid alternative, especially if you're looking for Texas-only compounded semaglutide at $149/mo, plus brand options.

Choose MedLeanRx if…

You want Texas-only compounded semaglutide at $149/mo, plus brand options and a starting price around $149/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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Broadest drug catalog in the Lion MD white-label cluster

8.1

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8.0

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MedLeanRx vs Vytora Health: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.