MD Trim Clinic vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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MD Trim Clinic
Best for: DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea
Visit MD Trim Clinic →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →MD Trim Clinic and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts at $149/mo, and Amazon One Medical edges ahead overall (8.7 vs 5.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MD Trim Clinic
Pricing not publicly listed.
Amazon One Medical
What’s included
MD Trim Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Billed separately
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MD Trim Clinic
5.8/10
Amazon One Medical
8.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MD Trim Clinic | Amazon One Medical |
|---|---|---|
| Starting Price | — | $149/mo |
| Features | ✓8 features | 6 features |
| States Available | 2 | ✓50 |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MD Trim Clinic
MD Trim Clinic is a small physician-led practice in Phoenix, AZ and Novato, CA offering compounded semaglutide and tirzepatide via telehealth and in-person visits. Medications are dispensed from LegitScript-certified pharmacies with B12 added to reduce nausea, and programs are tiered by weekly dose (Level 1 / Level 2). Led by Dr. Brandon Shaw, D.O. and nurse practitioner Andrea Farris, N.P., the clinic includes free initial screening, physician-guided dosing titration, and ongoing team support.
Read our full MD Trim Clinic review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
MD Trim Clinic
What we like
- Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
- Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
- Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
- Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
- Partnered mobile IV services available for enhanced nausea management and hydration support
Watch-outs
- Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
- Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
- No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
- Small practice with limited online presence and no published patient reviews or outcomes data
- No labs, coaching, or monitoring protocols disclosed on the site
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out MD Trim Clinic with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. MD Trim Clinic remains a solid alternative, especially if you're looking for DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.
Choose MD Trim Clinic if…
You want DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
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Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.