MangoRx vs PlexusDx
In our scoring, PlexusDx edges ahead overall (7.0 vs 5.5 out of 10).
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Key differences
- Price
- MangoRx $299/mo for oral compounded semaglutide; PlexusDx $129/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- PlexusDx 50 states (MangoRx doesn't publish a state list)
- Included
- MangoRx: medication, clinician visits; PlexusDx: medication, clinician visits
MangoRx
Affiliate partnerBest for men's-health shoppers who want oral compounded semaglutide at one flat price across doses
Oral compounded semaglutide
$299
$269.10 first month
Our score 5.5/10
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MangoRx
PlexusDx
Price
Semaglutide / month
Not listed
$129/mo
microdose plan
Tirzepatide / month
Not listed
$249/mo
starting dose
Oral semaglutide / month
$299/mo
$269.10 first month
Not listed
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Not listed
Included in the price
Medication, clinician visits
Medication, clinician visits
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Minimum commitment
None
Not disclosed
Refunds
Full refund if declined, else all sales final
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose MangoRx if…
- Lists oral compounded semaglutide, which PlexusDx doesn't price
- Men's-health telehealth that bundles GLP-1, TRT, ED, and hair care under one provider
What to weigh up
- No published state list; confirm yours at signup
- GLP-1 formulary, pricing tiers, states served, and pharmacy partners not yet confirmed
Choose PlexusDx if…
- Lists compounded semaglutide and compounded tirzepatide, which MangoRx doesn't price
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MangoRx
5.5/10
PlexusDx
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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From $249/mo
Get started →Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →ShedRx
Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
Read full review →From $299/mo (after intro offer)
Get started →MangoRx vs PlexusDx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to MangoRx and PlexusDx.
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