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LunaRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
LunaRx logo

LunaRx

7.3
★★★3.7/5

Best for: a GLP-1 program with muscle-protective peptides and a built-in taper

Visit LunaRx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

LunaRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

LunaRx

Starting — Lean Muscle Foundation stackCompounded
$199/mo
semaglutide

Published headline is "from $199/mo" for the entry Foundation stack (compounded semaglutide + muscle-protective peptides). Specific tier and tirzepatide pricing are confirmed only after a provider review; no per-dose price list is published.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

LunaRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

LunaRx

7.3/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureLunaRxNewSelf
Starting Price$199/mo$100/mo
Features8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNone1 warning

About LunaRx

LunaRx is a bilingual (English/Spanish) telehealth practice from LunaRx LLC built around "metabolic recomposition" — compounded GLP-1 therapy paired with muscle-protective peptides and a structured off-ramp taper, rather than an indefinite prescription. Programs start at $199/month; specific tier and tirzepatide pricing are confirmed only after a physician review. Care is physician-directed through an independent medical group (CareNexus Clinic PC), with $0 charged if you are not approved. Compounded medications are not FDA-approved.

Read our full LunaRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

LunaRx

What we like

  • Pairs GLP-1 with muscle-protective peptides (e.g., CJC-1295/Ipamorelin, NAD+) to defend lean mass during fat loss
  • Structured, physician-directed off-ramp taper with GI-reset support instead of an indefinite prescription
  • Bilingual care in English and Spanish across intake, messaging, and consults
  • Care directed through a named independent medical group (CareNexus Clinic PC); $0 charged if you are not approved
  • Published clinical support hours (Mon–Fri, CT) with phone, email, and secure messaging; cancel anytime
  • 503A compounded medications prepared in the USA and shipped discreetly to your door

Watch-outs

  • Only a "from $199/mo" starting price is published; tirzepatide and per-tier pricing are confirmed only after a provider review
  • Compounding pharmacy partners are not named on the site — a transparency gap
  • No LegitScript or PCAB verification is displayed
  • States served are not published; the site claims "telehealth nationwide" but the Terms limit service to states where LunaRx is licensed
  • Compounded medications are not FDA-approved (the site discloses this)
  • No refunds once medication is dispensed; order cancellations are only accepted within 24 hours
  • New brand with no independent Trustpilot or third-party rating; on-site testimonials only

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out LunaRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. LunaRx remains a solid alternative, especially if you're looking for a GLP-1 program with muscle-protective peptides and a built-in taper.

Choose LunaRx if…

You want a GLP-1 program with muscle-protective peptides and a built-in taper and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.8

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LGBTQ+-inclusive compounded GLP-1 telehealth

8.2

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Lab-monitored compounded GLP-1 with mandatory video visit

LunaRx vs NewSelf: FAQ

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