LunaRx vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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LunaRx
Best for: adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper
Visit LunaRx →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →LunaRx and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.7 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
LunaRx
Published headline is "from $199/mo" for the entry Foundation stack (compounded semaglutide + muscle-protective peptides). Specific tier and tirzepatide pricing are confirmed only after a provider review; no per-dose price list is published.
Amazon One Medical
What’s included
LunaRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
LunaRx
7.2/10
Amazon One Medical
8.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | LunaRx | Amazon One Medical |
|---|---|---|
| Starting Price | $199/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About LunaRx
LunaRx is a bilingual (English/Spanish) telehealth practice from LunaRx LLC built around "metabolic recomposition" — compounded GLP-1 therapy paired with muscle-protective peptides and a structured off-ramp taper, rather than an indefinite prescription. Programs start at $199/month; specific tier and tirzepatide pricing are confirmed only after a physician review. Care is physician-directed through an independent medical group (CareNexus Clinic PC), with $0 charged if you are not approved. Compounded medications are not FDA-approved.
Read our full LunaRx review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
LunaRx
What we like
- Pairs GLP-1 with muscle-protective peptides (e.g., CJC-1295/Ipamorelin, NAD+) to defend lean mass during fat loss
- Structured, physician-directed off-ramp taper with GI-reset support instead of an indefinite prescription
- Bilingual care in English and Spanish across intake, messaging, and consults
- Care directed through a named independent medical group (CareNexus Clinic PC); $0 charged if you are not approved
- Published clinical support hours (Mon–Fri, CT) with phone, email, and secure messaging; cancel anytime
- 503A compounded medications prepared in the USA and shipped discreetly to your door
Watch-outs
- Only a "from $199/mo" starting price is published; tirzepatide and per-tier pricing are confirmed only after a provider review
- Compounding pharmacy partners are not named on the site — a transparency gap
- No LegitScript or PCAB verification is displayed
- States served are not published; the site claims "telehealth nationwide" but the Terms limit service to states where LunaRx is licensed
- Compounded medications are not FDA-approved (the site discloses this)
- No refunds once medication is dispensed; order cancellations are only accepted within 24 hours
- New brand with no independent Trustpilot or third-party rating; on-site testimonials only
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out LunaRx with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. LunaRx remains a solid alternative, especially if you're looking for adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper.
Choose LunaRx if…
You want adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper and a starting price around $199/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
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Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $49/mo
Get started →LunaRx vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.