LifeRx.md vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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LifeRx.md
Best for: Budget patients wanting flat, dose-independent compounded GLP-1 pricing nationwide.
Visit LifeRx.md →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →LifeRx.md and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $200/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
LifeRx.md
NewSelf
All dosages same price
All dosages same price
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What’s included
LifeRx.md
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
LifeRx.md
7.1/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | LifeRx.md | NewSelf |
|---|---|---|
| Starting Price | $200/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓50 | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About LifeRx.md
LifeRx.md is a LegitScript-certified US telehealth provider offering customized weight loss with GLP-1s. It is known for flat, dose-independent compounded pricing: about $200 for a five-week supply of compounded semaglutide and $275 for compounded tirzepatide, with no increase as the dose climbs. Extra costs include roughly $30 shipping per order, a $49.95 initial consult and $25 follow-ups; effective monthly cost is around $255. Prescriptions are filled by state-licensed 503A pharmacies. An initial video consult is required. Available in all 50 states. HSA and FSA accepted.
Read our full LifeRx.md review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
LifeRx.md
What we like
- Flat pricing that does not rise with dose: semaglutide ~$200, tirzepatide ~$275 per 5-week supply
- LegitScript certified; prescriptions filled by state-licensed 503A pharmacies
- Available in all 50 states
- HSA and FSA payments accepted
- Required video telehealth consult ensures clinician oversight
Watch-outs
- Compounded GLP-1s are not FDA-approved for safety, efficacy or quality
- Extra fees stack up: ~$30 shipping, $49.95 initial consult, $25 follow-ups
- True monthly cost (~$255) is higher than the headline medication price
- Specific list of supported states not enumerated on site
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out LifeRx.md with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. LifeRx.md remains a solid alternative, especially if you're looking for Budget patients wanting flat, dose-independent compounded GLP-1 pricing nationwide..
Choose LifeRx.md if…
You want Budget patients wanting flat, dose-independent compounded GLP-1 pricing nationwide. and a starting price around $200/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Broadest drug catalog in the Lion MD white-label cluster
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Get started →LifeRx.md vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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