iThriveMD vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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iThriveMD
Best for: compounded GLP-1 within a lab-driven longevity and hormone clinic
Visit iThriveMD →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →iThriveMD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $299/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
iThriveMD
NewSelf
All dosages same price
All dosages same price
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What’s included
iThriveMD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
iThriveMD
7.3/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | iThriveMD | NewSelf |
|---|---|---|
| Starting Price | $299/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About iThriveMD
iThriveMD is a longevity and metabolic-health clinic (physical locations plus telehealth) offering compounded GLP-1 weight loss — semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing tirzepatide programs — alongside hormone therapy (HRT/TRT), NAD+, peptides, IV therapy, sexual health, and diagnostic lab testing. Care is lab-driven with personalized protocols and a free initial consultation; lower 'preferred pricing' is available to members. It publishes a thorough legal/policy suite. The compounding pharmacy is not named and no LegitScript certification is shown.
Read our full iThriveMD review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
iThriveMD
What we like
- Compounded semaglutide (from $299/mo) and tirzepatide (from $399/mo), plus microdosing tirzepatide programs
- Lab testing and personalized protocols with a medical team; free initial consultation
- Very thorough legal/policy suite (Terms, Privacy, EUA, Shipping, Returns, CCPA)
- Broad longevity menu: hormones (HRT/TRT), NAD+, peptides, IV therapy, sexual health, diagnostics
Watch-outs
- Premium pricing — higher than budget compounded-GLP-1 competitors (lowest rates need 'preferred pricing')
- Headline GLP-1 pricing is 'starting at'; full cost depends on dose and program length
- Compounding pharmacy partner not named
- Not LegitScript-certified (no certification displayed)
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out iThriveMD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. iThriveMD remains a solid alternative, especially if you're looking for compounded GLP-1 within a lab-driven longevity and hormone clinic.
Choose iThriveMD if…
You want compounded GLP-1 within a lab-driven longevity and hormone clinic and a starting price around $299/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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From $179/mo
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Oral-lozenge compounded GLP-1 access
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Get started →iThriveMD vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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