HumeCare+ vs Sesame Care
In our scoring, Sesame Care edges ahead overall (8.0 vs 7.2 out of 10).
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Key differences
- Price
- HumeCare+ $199/mo for compounded semaglutide; Sesame Care $349/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- HumeCare+ 46 states + DC (Sesame Care doesn't publish a state list)
- Included
- HumeCare+: medication, clinician visits; Sesame Care: not stated
HumeCare+
Affiliate partnerBest for GLP-1 weight loss with real-time body-composition tracking to protect muscle
semaglutide
$199
Our score 7.2/10
Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HumeCare+
Sesame Care
Price
Semaglutide / month
$199/mo
Not listed
Tirzepatide / month
$299/mo
Not listed
Oral semaglutide / month
$199/mo
Not listed
Brand Wegovy / Ozempic / month
Not listed
$349/mo
$199 first month
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
46 states + DC
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits
Not disclosed
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Video visit
Not disclosed
Required
Cancel anytime
Yes
Yes
Minimum commitment
None
None
Refunds
Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.
Not disclosed
Early-cancellation fee
None
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: HumeCare+ · Sesame Care
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HumeCare+ if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Sesame Care doesn't price
- Publishes its full state list (46 states + DC)
- Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
What to weigh up
- No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted
- Tirzepatide is sold only as a B12 + glycine combination — there is no plain tirzepatide option
Choose Sesame Care if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which HumeCare+ doesn't price
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
- BBB-accredited and LegitScript-certified
What to weigh up
- No published state list; confirm yours at signup
- Marketplace model means clinician credentials and quality vary provider to provider
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HumeCare+
7.2/10
Sesame Care
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →HumeCare+ vs Sesame Care: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.