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He & She MD vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
He & She MD logo

He & She MD

7.5
★★★3.8/5

Best for: Cheapest per-month GLP-1 if you can prepay a full year

Visit He & She MD
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx

He & She MD and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

He & She MD

Injectable (annual plan)Compounded
$99/mo
semaglutide

Annual plan: billed $1,188 upfront. Advertised as a limited-time rate (banner: 'Injectable Semaglutide $199/month from just $99/month').

Injectable (6-month plan)Compounded
$139/mo
semaglutide

Billed $834 every 6 months, saving $360 vs monthly. Homepage GLP-1 Platinum starter rate: $139/mo for the first 6 months, then renews at $1,194 per 6 months, equivalent to $199/mo.

Injectable (3-month plan)Compounded
$149/mo
semaglutide

Billed $447 every 3 months, saving $270 vs monthly.

Injectable (month-to-month)Compounded
$199/mo
semaglutide

Billed monthly; the standing rate every term plan discounts from.

Oral (6-month starter rate)Compounded · oral
$199/mo
semaglutide

GLP-1 Platinum oral: $199/mo for the first 6 months, then renews at $1,434 per 6 months, equivalent to $239/mo. Oral is not on the /weight-loss/plans term ladder; figures from the homepage program cards and footnote 3.

Injectable (annual plan)Compounded
$159/mo
tirzepatide

Annual plan: billed $1,908 upfront.

Injectable (6-month plan)Compounded
$199/mo
tirzepatide

Billed $1,194 every 6 months, saving $540 vs monthly. Homepage GLP-1 Platinum starter rate: $199/mo to start, then renews at $1,734 per 6 months, equivalent to $289/mo.

Injectable (3-month plan)Compounded
$209/mo
tirzepatide

Billed $627 every 3 months, saving $270 vs monthly.

Injectable (month-to-month)Compounded
$299/mo
tirzepatide

Billed monthly; the standing rate.

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

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What’s included

He & She MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

He & She MD

7.5/10

Overall

CoreAge Rx

8.3/10

Value25%

7.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.5

Trust & Safety15%

7.3A
vs
B
7.8

Accessibility10%

7.5A
vs
B
8.0

Support10%

7.9A
vs
B
8.4

Features & Coverage

FeatureHe & She MDCoreAge Rx
Starting Price$99/mo$99/mo
Features8 features6 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About He & She MD

He & She MD is a nationwide cash-pay telehealth clinic prescribing compounded semaglutide and tirzepatide, injectable or oral, plus brand-name access to Ozempic, Wegovy and Zepbound. Injectable semaglutide is $199/month billed monthly, falling to $139 on a six-month plan and $99 on the annual plan, prepaid for the year; tirzepatide runs $299/month down to $159 annually. Plans bundle medication, injection supplies, free shipping, unlimited provider messaging and GLP-1 coaching, and you are charged only if a clinician prescribes. Ships everywhere except Louisiana. LegitScript-certified.

Read our full He & She MD review →

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

He & She MD

What we like

  • Injectable semaglutide from $99/month on the annual plan, or $139/month on a six-month plan
  • Compounded semaglutide and tirzepatide, injectable or oral, plus brand access to Ozempic, Wegovy, Zepbound
  • Only charged if medication is prescribed, and no membership fees
  • Every plan includes medication, injection supplies, free shipping and unlimited provider messaging
  • GLP-1 coaching, nutrition guidance, and in-app progress tracking
  • LegitScript-certified, and it names both compounding pharmacies it uses
  • Ships to 49 states (all except Louisiana)

Watch-outs

  • Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
  • Does not ship to Louisiana or to PO boxes
  • The $99 and $159 headline rates require a full year prepaid in a single charge
  • Month-to-month costs $199 for semaglutide and $299 for tirzepatide, roughly double the annual rate
  • Six-month starter rates step up on renewal: semaglutide $139 to $199, tirzepatide $199 to $289
  • Cash-pay model, insurance billing not indicated

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out He & She MD with a higher overall score of 8.3/10 and is particularly strong for best overall value. He & She MD remains a solid alternative, especially if you're looking for Cheapest per-month GLP-1 if you can prepay a full year.

Choose He & She MD if…

You want Cheapest per-month GLP-1 if you can prepay a full year and a starting price around $99/mo.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

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Compounded GLP-1/GIP combo on a yearly plan with free shipping

6.9

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Budget-conscious shoppers

He & She MD vs CoreAge Rx: FAQ

He & She MD and CoreAge Rx have the same lowest ongoing monthly price of $99/mo, so price alone won't separate them — compare what each plan includes instead.
CoreAge Rx scores higher overall at 8.3/10 versus 7.5/10, and is particularly strong for best overall value. That said, He & She MD is a better fit if you want Cheapest per-month GLP-1 if you can prepay a full year.
He & She MD and CoreAge Rx both list availability in 50 states.
Both He & She MD and CoreAge Rx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
He & She MD and CoreAge Rx list the same lowest price for Semaglutide: $99/mo.

Key terms, explained

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Continue exploring He & She MD and CoreAge Rx head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.