He & She MD vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.5 out of 10).
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Key differences
- Price
- He & She MD $149/mo on a 3-month prepaid plan; Vytora Health $179/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- He & She MD 49 states + DC; Vytora Health 50 states + DC (only Vytora Health: Louisiana)
- Included
- He & She MD: medication, clinician visits, shipping, coaching; Vytora Health: medication, clinician visits, shipping
He & She MD
Best for Low per-month GLP-1 pricing if you can prepay 3 to 12 months
semaglutide
$149
on a 3-month prepaid plan
Our score 7.5/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
He & She MD
Vytora Health
Price
Semaglutide / month
$149/mo
on a 3-month prepaid plan
$179/mo
Semaglutide / year (modeled)
$1,788
$2,148
Tirzepatide / month
$209/mo
on a 3-month prepaid plan
$249/mo
Tirzepatide / year (modeled)
$2,508
$2,988
Oral semaglutide / month
$239/mo
$209 first month
Not listed
Oral tirzepatide / month
$299/mo
$269 first month
Not listed
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
49 states + DC
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
Prepaid plan terms of 3, 6 or 12 months; no month-to-month plan shown
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (1 state)
- Louisiana
Every dose and plan: He & She MD · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose He & She MD if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Vytora Health doesn't price
- Compounded semaglutide and tirzepatide as injections or oral, plus brand access to Ozempic, Wegovy and Zepbound
- Only charged if medication is prescribed, and no membership fees
What to weigh up
- Its $149/mo compounded semaglutide price needs a 3-month prepaid plan
- Not available in Louisiana
Choose Vytora Health if…
- Its $179/mo compounded semaglutide price needs no prepay; He & She MD's $149 needs a 3-month prepay
- Lists brand-name Zepbound / Mounjaro, which He & She MD doesn't price
- Serves Louisiana, where He & She MD doesn't
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
He & She MD
7.5/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →He & She MD vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.