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Glow vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Glow logo

Glow

7.1
★★★★☆3.6/5

Best for: people who want a compounded GLP-1 plan paired with an AI coach for daily accountability

Visit Glow →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

Glow and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Glow

Monthly plan, weekly injection with B6/B12Compounded
$199$99/mo
Save 50% right now
semaglutide

$99 for the first month, then $199 a month. An oral version is listed without a price

Monthly plan, weekly injection with B6/B12Compounded
$349$199/mo
Save 43% right now
tirzepatide

$199 for the first month, then $349 a month. An oral version is listed without a price

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Glow

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Glow

7.1/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

6.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureGlowNewSelf
Starting Price$199/mo✓$100/mo
Features✓7 features6 features
States Available46✓49
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted✓ Yes—
FDA Warnings✓None1 warning

About Glow

Glow is an AI weight-loss coach app from Endo Health, a San Francisco company, that also runs a separate compounded GLP-1 program. Physicians review your assessment by video or message, and two named pharmacies dispense. Semaglutide is $99 for the first month and then $199 a month; tirzepatide is $199, then $349. Enrollment starts in the Glow app, not on the website.

Read our full Glow review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Glow

What we like

  • Prices are on the homepage: semaglutide is $99 for the first month, then $199 a month
  • The price covers the physician consultation, the medication and free shipping, with no insurance needed
  • Names both dispensing pharmacies, with their addresses and phone numbers
  • Offers semaglutide and tirzepatide injections, with oral versions also listed
  • Physician visits can be by video or by message, and the site says assessments are reviewed within 24 hours
  • Pairs with the Glow AI coach for meal plans and check-ins by call or text, sold separately
  • Publishes a support phone number, and HSA or FSA cards are accepted

Watch-outs

  • The $99 and $199 prices are first-month offers; semaglutide then costs $199 a month and tirzepatide $349
  • Enrollment happens inside the Glow app, so you cannot see the checkout or billing terms on the website
  • The site does not name the medical group whose physicians prescribe
  • Medication refunds go through the dispensing pharmacy, and shipped medication generally cannot be returned
  • Oral semaglutide and tirzepatide are listed without a price
  • Not available in Alaska, Hawaii, North Carolina or South Carolina
  • The AI coach is a separate paid app subscription billed through Apple or Google
  • Only compounded medication is offered, with no brand-name Wegovy or Zepbound option

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Glow with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Glow remains a solid alternative, especially if you're looking for people who want a compounded GLP-1 plan paired with an AI coach for daily accountability.

Choose Glow if…

You want people who want a compounded GLP-1 plan paired with an AI coach for daily accountability and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

8.3

Collective

The lowest flat medication price if you can absorb an annual membership fee

Glow vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $199/mo for Glow. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.1/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Glow is a better fit if you want people who want a compounded GLP-1 plan paired with an AI coach for daily accountability.
NewSelf covers more — 49 states versus 46.
Neither Glow nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Glow is cheaper at $99/mo versus $100/mo at NewSelf.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Glow and NewSelf head-to-heads in the same category.

Or see the full category ranking.

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