Fifty 410 vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Fifty 410
Best for: Budget-focused buyers wanting transparent no-membership compounded GLP-1 pricing
Visit Fifty 410 →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Fifty 410 and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Fifty 410 starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Fifty 410
NewSelf
All dosages same price
All dosages same price
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What’s included
Fifty 410
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Fifty 410
7.0/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Fifty 410 | NewSelf |
|---|---|---|
| Starting Price | ✓$99/mo | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Fifty 410
Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B pharmacies. It uses a no-membership, pay-as-you-go model with transparent public pricing: semaglutide from 99 dollars per month and tirzepatide starter from 133 dollars per month, plus a high-dose tier. Provider reviews finish in 24 to 48 hours and free shipping arrives in one to two days. Cash-pay only; no direct insurance billing, but accepts FSA/HSA, Afterpay, and Affirm.
Read our full Fifty 410 review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Fifty 410
What we like
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
- Accepts FSA/HSA plus Afterpay and Affirm
Watch-outs
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Fifty 410 with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Fifty 410 remains a solid alternative, especially if you're looking for Budget-focused buyers wanting transparent no-membership compounded GLP-1 pricing.
Choose Fifty 410 if…
You want Budget-focused buyers wanting transparent no-membership compounded GLP-1 pricing and a starting price around $99/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Trimi Health
Budget-conscious shoppers
From $99/mo
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Mainstream telehealth GLP-1 access
From $149/mo
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Mainstream telehealth GLP-1 access
From $99/mo
Get started →Fifty 410 vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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