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Fierce Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Fierce Health logo

Fierce Health

6.9
★★★3.5/5

Best for: compounded GLP-1 with standard and microdose protocols plus a longevity catalog

Visit Fierce Health
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Fierce Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $undefined/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Fierce Health

$/mo
$/mo
$/mo
$/mo
$/mo

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Fierce Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Fierce Health

6.9/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureFierce HealthNewSelf
Starting Price$/mo$100/mo
Features5 features6 features
States Available3049
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings5 warningsNone

About Fierce Health

Fierce Health is a direct-to-consumer telehealth brand selling compounded semaglutide and tirzepatide in both standard and microdose programs, alongside a longevity catalog. Its four-program GLP-1 ladder is broader than peers that sell only one or two SKUs, with a microdose tier among the lower entry points. Pricing runs $197–$497/mo; service is limited to 30 enumerated states, and it's LegitScript Certified.

Read our full Fierce Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Fierce Health

What we like

  • 30-state service list spelled out in the Terms — buyers can verify eligibility before intake
  • LegitScript Certified
  • Publishes the FDA compounded-medication disclaimer on every product page
  • Four GLP-1 programs (standard and microdose semaglutide and tirzepatide) — a broader ladder than peers
  • Microdose tier at $197/mo is one of the lower entry points we've seen
  • Explicit refund policy if they can't ship to your state
  • Monthly, 3-month, and 6-month subscription options

Watch-outs

  • No named 503A compounding pharmacy partner — only generic 'partner pharmacies' language
  • Operating LLC name not disclosed anywhere on the site
  • Tirzepatide weight-loss program ($497/mo) showing 'sold out or unavailable' across all plans at review time
  • Clinical provider network not named
  • Sells gray-market longevity products (ivermectin, methylene blue) alongside GLP-1s — an unusual category mix
  • Only LegitScript — no PCAB, BBB, or NABP .pharmacy presence
  • Tirzepatide tier at $497/mo is at the high end of the segment
  • Compounded semaglutide and tirzepatide are not FDA-approved

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Fierce Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Fierce Health remains a solid alternative, especially if you're looking for compounded GLP-1 with standard and microdose protocols plus a longevity catalog.

Choose Fierce Health if…

You want compounded GLP-1 with standard and microdose protocols plus a longevity catalog and a starting price around $undefined/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Fierce Health vs NewSelf: FAQ

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