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Factor Health MD vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Factor Health MD logo

Factor Health MD

6.4
★★★☆☆3.2/5

Best for: broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide

Visit Factor Health MD
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Factor Health MD and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Factor Health MD starts lower at $99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Factor Health MD

Starting tier (all 3 GLP-1s)Compounded
$99/mo
semaglutide
Tirzepatide Plus (standard)Compounded
$149/mo
tirzepatide
Liraglutide (compounded)Compounded
$150/mo
semaglutide

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Factor Health MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Factor Health MD

6.4/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

6.0A
vs
B
8.5

User Experience15%

6.0A
vs
B
8.0

Trust & Safety15%

6.3A
vs
B
8.8

Accessibility10%

7.0A
vs
B
9.5

Support10%

6.0A
vs
B
8.0

Features & Coverage

FeatureFactor Health MDAmazon One Medical
Starting Price$99/mo$149/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Factor Health MD

Factor Health MD is a Florida-based multi-vertical telehealth platform with an unusually broad GLP-1 lineup — compounded semaglutide, tirzepatide, and the rarely offered liraglutide — plus longevity, vitamin injectables, and men's health products. Its standout is that three-molecule menu with an "all doses included" promise and no per-dose price escalation. GLP-1 therapy starts at $99/mo; HSA/FSA cards accepted.

Read our full Factor Health MD review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Factor Health MD

What we like

  • Three-GLP-1 lineup including liraglutide — rare in DTC and useful for patients sensitive to newer molecules
  • Aggressive $99/mo starting tier with all doses included
  • Multi-product platform (GLP-1, longevity, vitamin injectables, men's health, bundles)
  • HSA/FSA accepted — uncommon for compounded GLP-1
  • St. Petersburg, FL location and phone (305-930-8817) for accountability
  • LegitScript verification badge displayed
  • Free medical consultations
  • Price doesn't increase per dose as patients titrate up

Watch-outs

  • 503A/503B pharmacy partner not named
  • Full states-served list not disclosed
  • No named medical director
  • FDA compounded-medication disclaimer not prominently displayed
  • Corporate legal entity not disclosed
  • Governing law and arbitration venue not disclosed
  • Compounded liraglutide has a weaker weight-loss evidence base than semaglutide or tirzepatide
  • Tirzepatide tier ($149/mo) less prominent than the advertised $99 starting price

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Factor Health MD with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Factor Health MD remains a solid alternative, especially if you're looking for broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide.

Choose Factor Health MD if…

You want broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide and a starting price around $99/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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Factor Health MD vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.