Enhance MD vs Live Vital
In our scoring, Enhance MD edges ahead overall (8.2 vs 7.7 out of 10), and Live Vital costs less for compounded semaglutide (about $984 a year less).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- Live Vital $130/mo vs Enhance MD $212/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $984 a year less with Live Vital)
- Coverage
- Enhance MD 39 states; Live Vital 50 states (only Live Vital: Alabama, Arkansas, Georgia and 8 more)
- Included
- Enhance MD: medication, clinician visits, labs; Live Vital: medication, clinician visits, shipping
Enhance MD
Affiliate partnerBest for lab-monitored compounded GLP-1 with mandatory video visit
semaglutide
$212
$112 first month
Our score 8.2/10

Live Vital
Affiliate partnerBest for low-cost, physician-led compounded GLP-1 with peptide and hormone options
semaglutide
$130
$99 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Enhance MD
Live Vital
Price
Semaglutide / month
$212/mo
$112 first month
Better on this row: $130/mo
$99 first month
Semaglutide / year (modeled)
$2,544
Better on this row: $1,560
Tirzepatide / month
Better on this row: $169/mo
$239/mo
$183 first month
Tirzepatide / year (modeled)
Better on this row: $2,028
$2,868
Coverage
State availability
39 states
50 states
Included in the price
Medication, clinician visits, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Better on this row: Not required
Video visit
Required
Better on this row: Not required
Cancel anytime
Yes
Yes
Minimum commitment
None
Sold as 10-week protocols
Refunds
Not disclosed
Terms section 7: 'You may cancel at any time. Cancellation will be effective at the end of your current billing period. Refunds for consultations are provided at our discretion. Medications and lab work are generally non-refundable once ordered or dispensed.'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only Live Vital (11 states)
- Alabama
- Arkansas
- Georgia
- Hawaii
- Louisiana
- Mississippi
- Missouri
- North Dakota
- South Carolina
- Tennessee
- West Virginia
Every dose and plan: Enhance MD · Live Vital
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Enhance MD if…
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
What to weigh up
- About $984 a year more than Live Vital for compounded semaglutide
- Not available in 11 states that Live Vital serves

Choose Live Vital if…
- About $984 a year less than Enhance MD for compounded semaglutide at standing prices
- Serves 11 states that Enhance MD doesn't
- No lab work required to start; No video visit required
What to weigh up
- The advertised '/mo' rate divides a 10-week protocol by three, so a calendar month really costs about $130 or $239
- Doesn't accept insurance (HSA/FSA funds only)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Enhance MD
8.2/10
Live Vital
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Enhance MD vs Live Vital: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Enhance MD and Live Vital head-to-heads in the same category.
- Enhance MD vs Found
- Enhance MD vs Ivim Health
- Enhance MD vs Hims
- Live Vital vs Amazon One Medical
- Live Vital vs Vytora Health
- Live Vital vs CoreAge Rx
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.