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Enhance MD vs HumeCare+

In our scoring, Enhance MD edges ahead overall (8.2 vs 7.2 out of 10), and HumeCare+ costs less for compounded semaglutide (about $156 a year less).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
HumeCare+ $199/mo vs Enhance MD $212/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $156 a year less with HumeCare+)
Coverage
Enhance MD 39 states; HumeCare+ 46 states + DC (only HumeCare+: District of Columbia, Georgia, Hawaii and 5 more)
Included
Enhance MD: medication, clinician visits, labs; HumeCare+: medication, clinician visits

How we compare providers

Enhance MD logo

Enhance MD

Affiliate partner

Best for lab-monitored compounded GLP-1 with mandatory video visit

semaglutide

$212/mo

$112 first month

Our score 8.2/10

HumeCare+ logo

HumeCare+

Affiliate partner

Best for GLP-1 weight loss with real-time body-composition tracking to protect muscle

semaglutide

$199/mo

Our score 7.2/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Enhance MD

HumeCare+

Price

Semaglutide / month

$212/mo

$112 first month

Better on this row: $199/mo

Semaglutide / year (modeled)

$2,544

Better on this row: $2,388

Tirzepatide / month

Better on this row: $169/mo

$299/mo

Tirzepatide / year (modeled)

Better on this row: $2,028

$3,588

Oral semaglutide / month

Not listed

$199/mo

Coverage

State availability

39 states

46 states + DC

Oral option listed

Not listed

Yes

Included in the price

Medication, clinician visits, labs

Medication, clinician visits

Terms & safety

Price shown

Before intake

Plan quoted after intake; a price is published

Lab work

Required

Not disclosed

Video visit

Required

Not disclosed

Cancel anytime

Yes

Yes

Minimum commitment

None

None

Refunds

Not disclosed

Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.

Early-cancellation fee

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

August 2026

Show where they differ by state

Only HumeCare+ (7 states + DC)

  • District of Columbia
  • Georgia
  • Hawaii
  • Missouri
  • North Dakota
  • South Carolina
  • Tennessee
  • West Virginia

Every dose and plan: Enhance MD · HumeCare+

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Enhance MD logo

Choose Enhance MD if…

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)

What to weigh up

  • About $156 a year more than HumeCare+ for compounded semaglutide
  • Not available in 7 states + DC that HumeCare+ serves
HumeCare+ logo

Choose HumeCare+ if…

  • About $156 a year less than Enhance MD for compounded semaglutide at standing prices
  • Lists oral compounded semaglutide, which Enhance MD doesn't price
  • Serves 7 states + DC that Enhance MD doesn't

What to weigh up

  • No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted
  • Tirzepatide is sold only as a B12 + glycine combination — there is no plain tirzepatide option

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Enhance MD

8.2/10

Overall

HumeCare+

7.2/10

Value25%

7.0A
vs
B
7.5

Effectiveness25%

9.0A
vs
B
7.0

User Experience15%

8.5A
vs
B
7.5

Trust & Safety15%

8.0A
vs
B
6.8

Accessibility10%

8.5A
vs
B
7.0

Support10%

8.9A
vs
B
7.4

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Enhance MD vs HumeCare+: FAQ

For compounded semaglutide, HumeCare+ costs less: about $156 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo). See Costs & coverage above for each medication side by side.
Enhance MD scores higher overall at 8.2/10 versus 7.2/10, and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. That said, HumeCare+ is a better fit if you want GLP-1 weight loss with real-time body-composition tracking to protect muscle.
Both Enhance MD and HumeCare+ are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Enhance MD: $212, about $2,544 a year; first month $112. HumeCare+: $199, about $2,388 a year. HumeCare+ costs about $156 less a year at these prices.
Both serve 39 states. Only HumeCare+ serves District of Columbia, Georgia, Hawaii, Missouri, North Dakota, South Carolina and 2 more.
Enhance MD: cancel anytime — yes; minimum commitment — None; early-cancellation fee — not disclosed. HumeCare+: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. Check the provider's own terms before you buy.

Key terms, explained

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Continue exploring Enhance MD and HumeCare+ head-to-heads in the same category.

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