DudeMeds vs TrimRx
In our scoring, TrimRx edges ahead overall (7.7 vs 6.9 out of 10), and TrimRx costs less for compounded semaglutide (about $240 a year less).
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Key differences
- Price
- TrimRx $179/mo vs DudeMeds $199/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $240 a year less with TrimRx)
- Included
- DudeMeds: medication, clinician visits, shipping; TrimRx: medication, clinician visits, shipping
DudeMeds
Affiliate partnerBest for men seeking no-fee compounded or brand-name GLP-1 injections
semaglutide
$199
Our score 6.9/10
TrimRx
Affiliate partnerBest for best overall value
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
DudeMeds
TrimRx
Price
Semaglutide / month
$199/mo
Better on this row: $179/mo
$149 first month
Semaglutide / year (modeled)
$2,388
Better on this row: $2,148
Tirzepatide / month
Better on this row: $233/mo
$259/mo
Tirzepatide / year (modeled)
Better on this row: $2,796
$3,108
Brand Wegovy / Ozempic / month
$1,585/mo
on a 3-month prepaid plan
$1,579/mo
Brand Wegovy / Ozempic / year (modeled)
$19,020
$18,948
Brand Zepbound / Mounjaro / month
$1,350/mo
on a 3-month prepaid plan
$1,249/mo
Brand Zepbound / Mounjaro / year (modeled)
$16,200
$14,988
Coverage
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Yes
Not listed
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not required
Not disclosed
Cancel anytime
No
Not disclosed
Minimum commitment
3-month minimum
Not disclosed
Refunds
No refunds once shipped; damaged, wrong or late-dispatched items only
Not disclosed
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose DudeMeds if…
- Accepts FSA/HSA cards
- Compounded semaglutide and tirzepatide plus brand-name Ozempic, Wegovy, Mounjaro and Zepbound
- Every dose tier's price is listed on its product page before checkout
What to weigh up
- About $240 a year more than TrimRx for compounded semaglutide
- Weight-loss medication is injection-only, though the marketing page still mentions oral options
Choose TrimRx if…
- About $240 a year less than DudeMeds for compounded semaglutide at standing prices
- Its $1,579/mo brand-name Wegovy / Ozempic price needs no prepay; DudeMeds' $1,585 needs a 3-month prepay
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
What to weigh up
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
- Compounded semaglutide is not FDA-approved (the site discloses this) — it is not brand Wegovy or Ozempic
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
DudeMeds
6.9/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →DudeMeds vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.