Direct Meds vs Sprout Health
In our scoring, Sprout Health edges ahead overall (7.6 vs 6.4 out of 10), and Sprout Health costs less for compounded semaglutide (about $1,776 a year less).
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Key differences
- Price
- Sprout Health $149/mo vs Direct Meds $297/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,776 a year less with Sprout Health)
- Coverage
- Sprout Health 44 states (Direct Meds doesn't publish a state list)
- Included
- Direct Meds: medication, clinician visits, shipping; Sprout Health: medication
Direct Meds
Affiliate partnerAlso prices oral compounded semaglutide and oral compounded tirzepatide
semaglutide
$297
Our score 6.4/10
Sprout Health
Affiliate partnerBest for LegitScript-certified compounded GLP-1 via named pharmacies
semaglutide
$149
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
Sprout Health
Price
Semaglutide / month
$297/mo
Better on this row: $149/mo
Semaglutide / year (modeled)
$3,564
Better on this row: $1,788
Tirzepatide / month
$399/mo
Better on this row: $199/mo
Tirzepatide / year (modeled)
$4,788
Better on this row: $2,388
Oral semaglutide / month
$249/mo
Not listed
Oral tirzepatide / month
$299/mo
Not listed
Brand Wegovy / Ozempic / month
Not listed
$1,799/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,999/mo
Coverage
State availability
List not published
44 states
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Not disclosed
Minimum commitment
3-month prepay
Not disclosed
Refunds
Not disclosed
Non-refundable unless disqualified
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
1 warning letter
Provider facts checked
August 2026
August 2026
Every dose and plan: Direct Meds · Sprout Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Sprout Health doesn't price
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
What to weigh up
- 1 FDA warning letter on record
- About $1,776 a year more than Sprout Health for compounded semaglutide
Choose Sprout Health if…
- About $1,776 a year less than Direct Meds for compounded semaglutide at standing prices
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Direct Meds doesn't price
- Publishes its full state list (44 states)
What to weigh up
- 1 FDA warning letter on record
- Brand-name Wegovy and Zepbound cost $1,799 and $1,999 a month, far above its compounded prices
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
Sprout Health
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Direct Meds vs Sprout Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.