Direct Meds vs HealthRX
In our scoring, HealthRX edges ahead overall (7.3 vs 6.4 out of 10), and HealthRX costs less for compounded semaglutide (about $1,584 a year less).
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Key differences
- Price
- HealthRX $165/mo vs Direct Meds $297/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,584 a year less with HealthRX)
- Included
- Direct Meds: medication, clinician visits, shipping; HealthRX: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: Direct Meds 1, HealthRX none
Direct Meds
Affiliate partnerAlso prices oral compounded semaglutide and oral compounded tirzepatide
semaglutide
$297
Our score 6.4/10
HealthRX
Affiliate partnerBest for flat-price compounded GLP-1, LegitScript-certified cash-pay program
semaglutide
$165
Our score 7.3/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
HealthRX
Price
Semaglutide / month
$297/mo
Better on this row: $165/mo
Semaglutide / year (modeled)
$3,564
Better on this row: $1,980
Tirzepatide / month
$399/mo
Better on this row: $214/mo
Tirzepatide / year (modeled)
$4,788
Better on this row: $2,568
Oral semaglutide / month
$249/mo
Not listed
Oral tirzepatide / month
$299/mo
Not listed
Coverage
Oral option listed
Yes
Not listed
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month prepay
None
Refunds
Not disclosed
Refund if not approved; unshipped doses refunded
Early-cancellation fee
Yes
Better on this row: None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Direct Meds · HealthRX
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which HealthRX doesn't price
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
What to weigh up
- 1 FDA warning letter on record
- About $1,584 a year more than HealthRX for compounded semaglutide
Choose HealthRX if…
- About $1,584 a year less than Direct Meds for compounded semaglutide at standing prices
- Cancel anytime; No early-cancellation fee
- No FDA warning letters on record (Direct Meds has 1)
What to weigh up
- Doesn't publicly name its 503A compounding pharmacy — you can't check that part of the supply chain yourself
- Claims service in all 50 states but publishes no per-state list, so you learn eligibility only after the assessment
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
HealthRX
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →Direct Meds vs HealthRX: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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