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Direct Meds vs HealthRX

In our scoring, HealthRX edges ahead overall (7.3 vs 6.4 out of 10), and HealthRX costs less for compounded semaglutide (about $1,584 a year less).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
HealthRX $165/mo vs Direct Meds $297/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,584 a year less with HealthRX)
Included
Direct Meds: medication, clinician visits, shipping; HealthRX: medication, clinician visits, shipping
Safety
FDA warning letters on record: Direct Meds 1, HealthRX none

How we compare providers

Direct Meds logo

Direct Meds

Affiliate partner

Also prices oral compounded semaglutide and oral compounded tirzepatide

semaglutide

$297/mo

Our score 6.4/10

HealthRX

Affiliate partner

Best for flat-price compounded GLP-1, LegitScript-certified cash-pay program

semaglutide

$165/mo

Our score 7.3/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Direct Meds

HealthRX

Price

Semaglutide / month

$297/mo

Better on this row: $165/mo

Semaglutide / year (modeled)

$3,564

Better on this row: $1,980

Tirzepatide / month

$399/mo

Better on this row: $214/mo

Tirzepatide / year (modeled)

$4,788

Better on this row: $2,568

Oral semaglutide / month

$249/mo

Not listed

Oral tirzepatide / month

$299/mo

Not listed

Coverage

Oral option listed

Yes

Not listed

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits, shipping

FSA/HSA accepted

Not listed

Yes

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

No

Better on this row: Yes

Minimum commitment

3-month prepay

None

Refunds

Not disclosed

Refund if not approved; unshipped doses refunded

Early-cancellation fee

Yes

Better on this row: None

FDA warning letters

1 warning letter

Better on this row: None on record

Provider facts checked

August 2026

August 2026

Every dose and plan: Direct Meds · HealthRX

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Direct Meds logo

Choose Direct Meds if…

  • Lists oral compounded semaglutide and oral compounded tirzepatide, which HealthRX doesn't price
  • All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
  • LegitScript Certified

What to weigh up

  • 1 FDA warning letter on record
  • About $1,584 a year more than HealthRX for compounded semaglutide

Choose HealthRX if…

  • About $1,584 a year less than Direct Meds for compounded semaglutide at standing prices
  • Cancel anytime; No early-cancellation fee
  • No FDA warning letters on record (Direct Meds has 1)

What to weigh up

  • Doesn't publicly name its 503A compounding pharmacy — you can't check that part of the supply chain yourself
  • Claims service in all 50 states but publishes no per-state list, so you learn eligibility only after the assessment

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Direct Meds

6.4/10

Overall

HealthRX

7.3/10

Value25%

6.0A
vs
B
7.8

Effectiveness25%

7.5A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.5

Trust & Safety15%

3.8A
vs
B
7.2

Accessibility10%

8.0A
vs
B
6.8

Support10%

6.9A
vs
B
7.0

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7.9

GobyMeds

No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle

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From $169/mo

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7.7

Ivim Health

Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership

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From $65/mo + membership

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

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From $247/mo

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Direct Meds vs HealthRX: FAQ

For compounded semaglutide, HealthRX costs less: about $1,584 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo). See Costs & coverage above for each medication side by side.
HealthRX scores higher overall at 7.3/10 versus 6.4/10. That said, Direct Meds remains a solid alternative.
Both Direct Meds and HealthRX are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Direct Meds: $297, about $3,564 a year. HealthRX: $165, about $1,980 a year. HealthRX costs about $1,584 less a year at these prices.
Direct Meds doesn't publish a state list. HealthRX doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
Direct Meds: cancel anytime — no; minimum commitment — 3-month prepay; early-cancellation fee — yes. HealthRX: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Direct Meds and HealthRX head-to-heads in the same category.

Or see the full category ranking.

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