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CoreAge Rx vs Yes Clinic

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★☆4.2/5

Best for: best overall value

Visit CoreAge Rx →
VS

Yes Clinic

7.8
★★★★☆3.9/5

Best for: flat per-dose pricing, and seeing every price without a quiz or an account

Visit Yes Clinic →

CoreAge Rx and Yes Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $129/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

same price at every dose

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

same price at every dose

Yes Clinic

3-month plan, $387 charged upfrontCompounded
$129/mo
semaglutide

$387 for 3 months = $129/mo. 6 months is $699 = $116.50/mo and is labelled "price locked". No single-month plan renders. Flat at every dose.

3-month plan, $447 charged upfrontCompounded
$149/mo
tirzepatide

$447 for 3 months and $894 for 6 months both work out at $149/mo, "price locked". No single-month plan renders. Flat at every dose.

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Yes Clinic

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Yes Clinic

7.8/10

Value25%

8.5A
vs
B
9.0

Effectiveness25%

8.5A
vs
B
8.0

User Experience15%

8.5A
vs
B
9.0

Trust & Safety15%

7.8A
vs
B
5.5

Accessibility10%

8.0A
vs
B
7.0

Support10%

8.4A
vs
B
6.5

Features & Coverage

FeatureCoreAge RxYes Clinic
Starting Price✓$99/mo$129/mo
Features6 features6 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-certified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Yes Clinic

Yes Clinic sells compounded semaglutide and tirzepatide at one flat price that does not rise as your dose is titrated up — $129/mo for semaglutide and $149/mo for tirzepatide, with the consultation, shipping and membership all at $0. Every price is published on the product page without a quiz or an account. The trade-off is that the smallest plan is a three-month prepay charged upfront.

Read our full Yes Clinic review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Yes Clinic

What we like

  • Flat price at every dose — $129/mo semaglutide, $149/mo tirzepatide, and it does not climb as you titrate
  • At $129/mo semaglutide sits only $20 below tirzepatide, so stepping up costs little
  • "Every price is on this page. No quiz and no account needed to see it" — no email wall to see cost
  • Consultation ($30), shipping and membership are all listed at $0: "the price on the tile is the whole price"
  • Full refund if you cancel before the pharmacy dispenses; cancel yourself from your account
  • Bilingual site with a working EN/ES toggle

Watch-outs

  • Smallest plan is a 3-month prepay — $387 or $447 charged upfront, not a monthly bill
  • Their live Terms of Use still contains an unfilled template placeholder: governed by the laws of the State of {GOVERNING_LAW_STATE}
  • No pharmacy partner is named despite a "LegitScript Certified" banner in the footer
  • No state list published: "Services are not available in all states"
  • Product pages served different prices in source HTML than they render, so quote the figure you see on screen
  • Support is email-only; no phone number published

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Yes Clinic with a higher overall score of 8.3/10 and is particularly strong for best overall value. Yes Clinic remains a solid alternative, especially if you're looking for flat per-dose pricing, and seeing every price without a quiz or an account.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose Yes Clinic if…

You want flat per-dose pricing, and seeing every price without a quiz or an account and a starting price around $129/mo.

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CoreAge Rx vs Yes Clinic: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $129/mo for Yes Clinic. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 7.8/10, and is particularly strong for best overall value. That said, Yes Clinic is a better fit if you want flat per-dose pricing, and seeing every price without a quiz or an account.
CoreAge Rx lists availability in 50 states, while Yes Clinic's state list is not publicly listed.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); Yes Clinic is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $129/mo at Yes Clinic.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring CoreAge Rx and Yes Clinic head-to-heads in the same category.

Or see the full category ranking.

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