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CoreAge Rx vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
He & She MD logo

He & She MD

7.5
★★★3.8/5

Best for: Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access

Visit He & She MD

CoreAge Rx and He & She MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, He & She MD starts lower at $99/mo versus $149/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Platinum microdose, intro (3-mo)Compounded
$99/mo
semaglutide
StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

He & She MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

He & She MD

7.5/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.5A
vs
B
7.5

Trust & Safety15%

7.8A
vs
B
7.3

Accessibility10%

8.0A
vs
B
7.5

Support10%

8.4A
vs
B
7.9

Features & Coverage

FeatureCoreAge RxHe & She MD
Starting Price$149/mo$99/mo
Features6 features8 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About He & She MD

He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name access to Ozempic, Wegovy and Zepbound. The GLP-1 Platinum program starts at $139/month introductory for injectables (then $199), with free expedited shipping, unlimited board-certified clinician access, GLP-1 coaching, and in-app progress tracking. You are only charged if medication is prescribed. Ships to all US states except Louisiana. LegitScript-certified.

Read our full He & She MD review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

He & She MD

What we like

  • Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
  • Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
  • Only charged if medication is prescribed; no hidden fees
  • Free expedited shipping and unlimited board-certified clinician access
  • GLP-1 coaching, nutrition guidance, and in-app progress tracking
  • LegitScript-certified with named FDA-registered pharmacy partners
  • Ships to 49 states (all except Louisiana)

Watch-outs

  • Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
  • Does not ship to Louisiana or to PO boxes
  • Introductory pricing rises after the 6-month (or 3-month microdose) plan
  • Cash-pay model — insurance billing not indicated

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out He & She MD with a higher overall score of 8.3/10 and is particularly strong for best overall value. He & She MD remains a solid alternative, especially if you're looking for Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Choose He & She MD if…

You want Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access and a starting price around $99/mo.

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7.6

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CoreAge Rx vs He & She MD: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.