Clume Health vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Clume Health
Best for: readers who want a separately priced microdose track and named dispensing pharmacies
Visit Clume Health →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Clume Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $219/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Clume Health
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.
The $200/mo figure requires a 12-week prepaid term.
The $200/mo figure requires a 12-week prepaid term.
NewSelf
All dosages same price
All dosages same price
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What’s included
Clume Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Clume Health
7.1/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Clume Health | NewSelf |
|---|---|---|
| Starting Price | $219/mo | ✓$100/mo |
| Features | 5 features | ✓6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About Clume Health
Clume Health sells compounded semaglutide and tirzepatide in oral and injectable form across three tiers: a full-dose Signature program from $259/mo, a Microdose/Maintain program from $219/mo, and an NAD+ and sermorelin longevity track. Its terms name four dispensing pharmacies outright, which most compounded sellers will not do. Clinical care runs through OpenLoop, and cheaper per-month rates are available only by prepaying a 12- or 52-week term.
Read our full Clume Health review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Clume Health
What we like
- Names four dispensing pharmacies in its terms, a level of disclosure most compounded sellers avoid.
- Offers both full-dose and microdose tracks, so maintenance has its own priced program.
- Sells semaglutide and tirzepatide in oral as well as injectable form.
- Lists what the monthly price covers, including consultation, medication and at-home delivery.
- Cancellation is allowed at any time by email or through the patient portal.
Watch-outs
- The homepage advertises "starting at *$199/month" and "*$159/month", but no program is priced at either figure.
- Those asterisks lead to no footnote anywhere on the page.
- The cheapest advertised rates require prepaying a full term — $186/mo means a 52-week commitment.
- Canceling needs 72 hours' notice before the next billing date or you are charged for that cycle.
- No refund is issued for the month in which you cancel, or for any prior month.
- Personalized options appear only after you accept OpenLoop's telehealth consent.
- No LegitScript seal or other verified trust badge appears anywhere on the site.
- Support is email only; no phone number or published hours.
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Clume Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Clume Health remains a solid alternative, especially if you're looking for readers who want a separately priced microdose track and named dispensing pharmacies.
Choose Clume Health if…
You want readers who want a separately priced microdose track and named dispensing pharmacies and a starting price around $219/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Budget-conscious shoppers
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Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
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Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →Clume Health vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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