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Clume Health vs Collective

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Clume Health logo

Clume Health

7.1
★★★3.6/5

Best for: readers who want a separately priced microdose track and named dispensing pharmacies

Visit Clume Health
VS
Collective logo

Collective

8.3
★★★★4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective

Clume Health and Collective are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $219/mo, and Collective edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Clume Health

Signature program, full dose — month-to-monthCompounded
$259/mo
semaglutide

The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.

Signature program, full dose — month-to-monthCompounded
$259/mo
tirzepatide

The $186/mo figure is a 52-week prepaid term, not an ongoing monthly rate.

Microdose/Maintain program — month-to-monthCompounded
$219/mo
semaglutide

The $200/mo figure requires a 12-week prepaid term.

Microdose/Maintain program — month-to-monthCompounded
$219/mo
tirzepatide

The $200/mo figure requires a 12-week prepaid term.

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

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What’s included

Clume Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Clume Health

7.1/10

Overall

Collective

8.3/10

Value25%

7.0A
vs
B
9.4

Effectiveness25%

7.5A
vs
B
8.2

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
7.2

Accessibility10%

7.0A
vs
B
7.4

Support10%

6.5A
vs
B
8.4

Features & Coverage

FeatureClume HealthCollective
Starting Price$219/mo$59/mo
Features5 features3 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Clume Health

Clume Health sells compounded semaglutide and tirzepatide in oral and injectable form across three tiers: a full-dose Signature program from $259/mo, a Microdose/Maintain program from $219/mo, and an NAD+ and sermorelin longevity track. Its terms name four dispensing pharmacies outright, which most compounded sellers will not do. Clinical care runs through OpenLoop, and cheaper per-month rates are available only by prepaying a 12- or 52-week term.

Read our full Clume Health review →

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

Pros & Cons

Clume Health

What we like

  • Names four dispensing pharmacies in its terms, a level of disclosure most compounded sellers avoid.
  • Offers both full-dose and microdose tracks, so maintenance has its own priced program.
  • Sells semaglutide and tirzepatide in oral as well as injectable form.
  • Lists what the monthly price covers, including consultation, medication and at-home delivery.
  • Cancellation is allowed at any time by email or through the patient portal.

Watch-outs

  • The homepage advertises "starting at *$199/month" and "*$159/month", but no program is priced at either figure.
  • Those asterisks lead to no footnote anywhere on the page.
  • The cheapest advertised rates require prepaying a full term — $186/mo means a 52-week commitment.
  • Canceling needs 72 hours' notice before the next billing date or you are charged for that cycle.
  • No refund is issued for the month in which you cancel, or for any prior month.
  • Personalized options appear only after you accept OpenLoop's telehealth consent.
  • No LegitScript seal or other verified trust badge appears anywhere on the site.
  • Support is email only; no phone number or published hours.

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Our Verdict

Winner: Collective

Collective edges out Clume Health with a higher overall score of 8.3/10 and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. Clume Health remains a solid alternative, especially if you're looking for readers who want a separately priced microdose track and named dispensing pharmacies.

Choose Clume Health if…

You want readers who want a separately priced microdose track and named dispensing pharmacies and a starting price around $219/mo.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

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8.2

Gala

Compounded GLP-1/GIP combo on a yearly plan with free shipping

6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

Clume Health vs Collective: FAQ

Key terms, explained

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