Calibrate Health vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Calibrate Health
Best for: year-long coaching wrap around insured branded GLP-1s
Visit Calibrate Health →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Calibrate Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Calibrate Health starts lower at $25/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Calibrate Health
$199/mo membership program fee; $597 total over the initial 3-month commitment, billed in monthly installments; renews monthly after; medication billed separately
typically $25/mo or less with insurance after any deductible; on top of the $199/mo program fee
NewSelf
All dosages same price
All dosages same price
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What’s included
Calibrate Health
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Calibrate Health
7.9/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Calibrate Health | NewSelf |
|---|---|---|
| Starting Price | ✓$25/mo | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | ✓50 | 49 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Calibrate Health
Calibrate Health is a year-long metabolic-reset program pairing branded GLP-1 medication (Wegovy, Ozempic, Zepbound, or Foundayo) with 1:1 video coaching and dietitian support — a deeper clinical wrap than transactional telehealth. It's branded-only, with a money-back guarantee tied to outcomes. The $199/month program fee runs separately from medication, which can drop to about $25/month with insurance and a savings card.
Read our full Calibrate Health review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Calibrate Health
What we like
- Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
- $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
- Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
- Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
- Money-back guarantee tied to a 10% weight-loss outcome over the program year
- Publishes 3-year outcomes data (19% mean weight loss)
Watch-outs
- Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
- Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
- Meaningfully more expensive than compounded telehealth if your insurance denies coverage
- Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
- Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Calibrate Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Calibrate Health remains a solid alternative, especially if you're looking for year-long coaching wrap around insured branded GLP-1s.
Choose Calibrate Health if…
You want year-long coaching wrap around insured branded GLP-1s and a starting price around $25/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →Calibrate Health vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.