CaliberRx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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CaliberRx
Best for: compounded GLP-1 from a compliance-thorough, fully online clinic
Visit CaliberRx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →CaliberRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
CaliberRx
Pricing not publicly listed.
NewSelf
All dosages same price
All dosages same price
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What’s included
CaliberRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CaliberRx
7.6/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | CaliberRx | NewSelf |
|---|---|---|
| Starting Price | — | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About CaliberRx
CaliberRx is a 100% online telehealth platform offering compounded GLP-1 weight-loss treatment — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review. It runs a no-insurance, free discreet delivery model with 24/7 medical support, and publishes an unusually thorough legal and compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, disclaimers). Pricing shows only after the intake quiz, compounded GLP-1s are not FDA-approved, the pharmacy is not named, and no LegitScript is displayed.
Read our full CaliberRx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
CaliberRx
What we like
- Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
- 100% online with free, discreet delivery and 24/7 medical support; no insurance required
- Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
- Personalized plan written by a licensed provider based on your individualized assessment
Watch-outs
- Pricing is not published — it is shown only after you complete the intake quiz
- Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
- State-availability list is not published
- No LegitScript certification displayed
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out CaliberRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. CaliberRx remains a solid alternative, especially if you're looking for compounded GLP-1 from a compliance-thorough, fully online clinic.
Choose CaliberRx if…
You want compounded GLP-1 from a compliance-thorough, fully online clinic.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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RNK Health
Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
Get started →Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →SkinnyRx
Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →CaliberRx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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