CaliberRx vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.6 out of 10), and Vytora Health costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- Vytora Health $179/mo vs CaliberRx $229/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with Vytora Health)
- Coverage
- CaliberRx 46 states + DC; Vytora Health 50 states + DC (only Vytora Health: Alabama, Massachusetts, Rhode Island and 1 more)
- Included
- CaliberRx: medication, clinician visits, shipping; Vytora Health: medication, clinician visits, shipping
CaliberRx
Best for compounded GLP-1 from a compliance-thorough, fully online clinic
semaglutide
$229
$199 first month
Our score 7.6/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
CaliberRx
Vytora Health
Price
Semaglutide / month
$229/mo
$199 first month
Better on this row: $179/mo
Semaglutide / year (modeled)
$2,748
Better on this row: $2,148
Tirzepatide / month
Better on this row: $229/mo
$199 first month
$249/mo
Tirzepatide / year (modeled)
Better on this row: $2,748
$2,988
Oral semaglutide / month
$229/mo
$199 first month
Not listed
Oral tirzepatide / month
$229/mo
$199 first month
Not listed
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
46 states + DC
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (4 states)
- Alabama
- Massachusetts
- Rhode Island
- Vermont
Every dose and plan: CaliberRx · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose CaliberRx if…
- Lists oral compounded semaglutide and oral compounded tirzepatide, which Vytora Health doesn't price
- Compounded semaglutide and tirzepatide, prescribed by licensed clinicians after an online medical-history review
- 100% online with free, discreet delivery and 24/7 medical support; no insurance required
What to weigh up
- About $600 a year more than Vytora Health for compounded semaglutide
- Not available in 4 states that Vytora Health serves
Choose Vytora Health if…
- About $600 a year less than CaliberRx for compounded semaglutide at standing prices
- Lists brand-name Zepbound / Mounjaro, which CaliberRx doesn't price
- Serves 4 states that CaliberRx doesn't
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CaliberRx
7.6/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo (+ required membership)
Get started →CoreAge Rx
Lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
Read full review →From $79/mo (“starting at” price)
Get started →CaliberRx vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.