Blis MD vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Blis MD
Best for: people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins
Visit Blis MD →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →Blis MD and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Blis MD starts lower at $139/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Blis MD
Flat monthly; includes medication and provider check-ins
Flat monthly; includes bi-weekly check-ins
Amazon One Medical
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What’s included
Blis MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Blis MD
7.0/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Blis MD | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$139/mo | $149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Blis MD
Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider. Pricing is transparent and flat: semaglutide is 139 dollars per month and tirzepatide is 199 dollars per month, each including a monthly medication supply, personalized dosing, and provider check-ins. Blis MD also markets other wellness peptides such as BPC-157, NAD plus, and Sermorelin. Compounded medications are not FDA-approved. Contact is by phone and email; specific states served are not published.
Read our full Blis MD review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Blis MD
What we like
- Transparent flat monthly pricing published upfront (139 dollars semaglutide, 199 dollars tirzepatide)
- Free initial virtual consultation with a licensed provider
- Both semaglutide and tirzepatide offered with ongoing provider check-ins
Watch-outs
- Compounding pharmacy is not named publicly
- States served are not listed on the site
- Thin public trust signals (no LegitScript seal or named medical director found)
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Blis MD with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Blis MD remains a solid alternative, especially if you're looking for people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins.
Choose Blis MD if…
You want people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins and a starting price around $139/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
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Get started →Blis MD vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.