Aspire Health vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Aspire Health
Best for: Nebraska telehealth: compounded + brand GLP-1s with labs included
Visit Aspire Health →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Aspire Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $205/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Aspire Health
Verbatim from weight-loss page: '$149' for 5-week supply of compounded semaglutide/B6 (low dose 0.25–0.5 mg) + $75/month LoseIt program fee = ~$205/month total. 'Medication costs are not included in either program fee.' 15-week supply listed at $399 (~$115/mo for medication alone). program fee enrollment fee $200 ($175 online).
Verbatim from weight-loss page: '$199' for 5-week supply of compounded semaglutide/B6 (high dose 1.7+ mg) + $75/month LoseIt program fee = ~$247/month total. 15-week supply listed at $499 (~$144/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$199' for 4-week supply of Wegovy (brand semaglutide, starter doses) + $75/month LoseIt program fee = ~$274/month total. Other Wegovy doses listed at $399/4 weeks (~$474/mo total with program fee). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$249' for 5-week supply of compounded tirzepatide/B6 (2.5 mg) + $75/month LoseIt program fee = ~$289/month total. 15-week supply at $699 (~$202/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$349' for 5-week supply of compounded tirzepatide/B6 (5–15 mg) + $75/month LoseIt program fee = ~$375/month total. 15-week supply at $999 (~$289/mo for medication alone). 'Medication costs are not included in either program fee.'
Verbatim from weight-loss page: '$299' for 4-week supply of Zepbound (brand tirzepatide, 2.5 mg) + $75/month LoseIt program fee = ~$374/month total. Higher doses (7.5–15 mg) listed at $449/4wks (~$524/mo total with program fee). 'Medication costs are not included in either program fee.'
NewSelf
All dosages same price
All dosages same price
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What’s included
Aspire Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Aspire Health
6.9/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Aspire Health | NewSelf |
|---|---|---|
| Starting Price | $205/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | ✓None | 1 warning |
About Aspire Health
Aspire Health is a Nebraska-based telehealth practice offering both compounded semaglutide/tirzepatide (formulated with B6) and brand-name Wegovy and Zepbound, prescribed by a named PA/NP clinical team. The LoseIt membership ($200 enrollment + $75/month) includes lab orders with interpretation, provider visits every 2–3 months, Slimpossible app access, and ongoing support — with medication billed separately starting at $149 per 5-week supply for compounded semaglutide.
Read our full Aspire Health review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Aspire Health
What we like
- Both compounded and brand-name options (Wegovy + Zepbound) — rare among GLP-1 telehealth providers
- Lab orders with interpretation included in LoseIt membership — not billed separately
- Named clinical team: founded by Jenni Haan, MPAS, PA-C (18+ years experience) with four additional credentialed providers
- Slimpossible app + secure messaging for ongoing support between provider visits
- HSA/FSA accepted; Cherry third-party financing available for patients needing payment plans
Watch-outs
- Membership fee ($75/month) stacks on top of separately billed medication — total spend $205–$524/month depending on dose
- No LegitScript certification or independent third-party accreditation disclosed
- States served not publicly listed; availability depends on individual provider licensure
- All medication sales are final once shipped; consultation fee non-refundable once completed
- Compounding pharmacy partner not named on any public page
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Aspire Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Aspire Health remains a solid alternative, especially if you're looking for Nebraska telehealth: compounded + brand GLP-1s with labs included.
Choose Aspire Health if…
You want Nebraska telehealth: compounded + brand GLP-1s with labs included and a starting price around $205/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $88/mo
Get started →Aspire Health vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.