Amazon One Medical vs YourHealthRx
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.9 out of 10).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. How we make money
Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; YourHealthRx $170/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Both serve the same 50 states
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); YourHealthRx: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
YourHealthRx
Best for Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up
semaglutide
$170
Our score 7.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
YourHealthRx
Price
Semaglutide / month
Not listed
$170/mo
Tirzepatide / month
Not listed
$210/mo
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Minimum commitment
Not disclosed
None (monthly plan available)
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · YourHealthRx
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which YourHealthRx doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
- Brand-name Wegovy, Zepbound and Foundayo prescribed by One Medical clinicians and filled by Amazon Pharmacy
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose YourHealthRx if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Compounded semaglutide and tirzepatide in two formats: weekly injectable or daily oral dissolving tablet
What to weigh up
- YourHealthRx is a platform, not the prescriber or pharmacy; prescribing runs through partner clinicians
- Compounded medications are not FDA-approved, and are not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Amazon One Medical and YourHealthRx in context
No medication appears on both price lists, so there is no fair price comparison to make. Amazon One Medical lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, while YourHealthRx lists compounded semaglutide and compounded tirzepatide. If you have not settled on a medication yet, our Wegovy page and semaglutide page cover what each one is approved for and what it costs. In our scoring, Amazon One Medical is at 8.5 and YourHealthRx at 7.9 out of 10.
Amazon One Medical prices only brand-name medication, while YourHealthRx sells compounded versions prepared by a pharmacy. That is a bigger difference than the monthly figure suggests, and our compounded vs brand-name decision guide walks through it. YourHealthRx states that its price stays the same at every dose. Amazon One Medical does not say either way, which matters once you titrate up; the flat-price GLP-1 list shows who else commits to one price. Only Amazon One Medical lists a pill (brand-name Wegovy pill / Rybelsus). If avoiding injections is the point, read our Wegovy pill guide before choosing on price.
The next head-to-head for Amazon One Medical is Amazon One Medical vs YOURx Health; YOURx Health sells semaglutide and tirzepatide and lists 49 states. For YourHealthRx, it is YourHealthRx vs Vytora Health; Vytora Health sells semaglutide and tirzepatide and lists 50 states + DC. If neither fits, the wider shortlists are alternatives to Amazon One Medical and alternatives to YourHealthRx.
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
YourHealthRx
7.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. How we make money
Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo (+ required membership)
Get started →CoreAge Rx
Lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
Read full review →From $79/mo (“starting at” price)
Get started →Amazon One Medical vs YourHealthRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and YourHealthRx head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- YourHealthRx vs Vytora Health
Or see the full category ranking, or alternatives to Amazon One Medical and YourHealthRx.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.