Amazon One Medical vs YOURx Health
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 6.6 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; YOURx Health $159/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states; YOURx Health 49 states (only Amazon One Medical: Mississippi)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); YOURx Health: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
YOURx Health
Best for self-pay buyers who want compounded GLP-1 injections or oral tablets at published prices
semaglutide
$159
Our score 6.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
YOURx Health
Price
Semaglutide / month
Not listed
$159/mo
Tirzepatide / month
Not listed
$179/mo
Oral semaglutide / month
Not listed
$139/mo
Oral tirzepatide / month
Not listed
$159/mo
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
49 states
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Not disclosed
Required
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None stated: 'You can pause or cancel your subscription anytime before your next shipment.'
Refunds
Not disclosed
'Prescription medications are not eligible for return once dispensed by the pharmacy.' Damaged, incorrect or misdispensed medication: contact within 30 days for review, replacement or refund. Consultation and membership fees are 'non-refundable once services have been rendered.'
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Amazon One Medical (1 state)
- Mississippi
Every dose and plan: Amazon One Medical · YOURx Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which YOURx Health doesn't price
- Serves Mississippi, where YOURx Health doesn't
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose YOURx Health if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Physician consultation, supplies, shipping and ongoing support listed as included
What to weigh up
- Not available in Mississippi
- Self-pay only; insurance is not accepted
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
YOURx Health
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Amazon One Medical vs YOURx Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.