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Amazon One Medical vs Trally Meds

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★☆4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical →
VS
Trally Meds logo

Trally Meds

6.8
★★★☆☆3.4/5

Best for: people who want published GLP-1 prices with free consultations and the option to buy one month at a time

Visit Trally Meds →

Amazon One Medical and Trally Meds are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $249/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

Trally Meds

1-month supply, auto-refills after each provider check-inCompounded
$249/mo
semaglutide

3-month supply $672 (about $224/mo). The site prices the month as four weeks: "Only $62.25 per week".

1-month supply, auto-refills after each provider check-inCompounded
$349/mo
tirzepatide

3-month supply $942 (about $314/mo). The site prices the month as four weeks: "Only $87.25 per week".

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Trally Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Trally Meds

6.8/10

Value25%

8.5A
vs
B
6.5

Effectiveness25%

8.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
6.0

Trust & Safety15%

8.8A
vs
B
5.5

Accessibility10%

9.5A
vs
B
7.0

Support10%

8.0A
vs
B
7.0

Features & Coverage

FeatureAmazon One MedicalTrally Meds
Starting Price✓$149/mo$249/mo
Features6 features✓7 features
States Available50Not disclosed
Compounded—✓ Yes
Brand Name✓ Yes—
FSA/HSA Accepted——
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About Trally Meds

Trally Meds is an online telehealth service with a Memphis, Tennessee address that sells compounded semaglutide and tirzepatide, along with hair loss, erectile dysfunction and anti-aging treatment. A 1-month supply costs $249 for semaglutide or $349 for tirzepatide, and a 3-month supply costs $672 or $942. Consultations and shipping are free, and plans renew automatically after each provider check-in.

Read our full Trally Meds review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Trally Meds

What we like

  • Prices are public before you sign up: $249 for a month of semaglutide and $349 for tirzepatide
  • Consultations and shipping are free, with no membership fee
  • Your card is only held, not charged, until a provider writes a prescription
  • Cancel anytime in the member portal, by phone or by email, with no cancellation fee
  • A 3-month supply lowers the cost to about $224 a month for semaglutide and $314 for tirzepatide
  • Publishes a support phone line with weekday hours

Watch-outs

  • The site does not say how often the 1-month supply renews, and its weekly price math treats a month as four weeks
  • Plans renew automatically until you cancel, and a charge that has already gone through is not refunded
  • All sales are final once your medication ships
  • The dispensing pharmacy is not named, and the site calls its pharmacies "FDA approved"
  • You must create an account with name, email, phone and a password before any health questions
  • The assessment page carries generic testimonials and calls the service "Telemed"
  • There are no independent customer reviews on Trustpilot yet

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Trally Meds with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Trally Meds remains a solid alternative, especially if you're looking for people who want published GLP-1 prices with free consultations and the option to buy one month at a time.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

Choose Trally Meds if…

You want people who want published GLP-1 prices with free consultations and the option to buy one month at a time and a starting price around $249/mo.

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7.6

SkinnyRx

Mainstream telehealth GLP-1 access

7.8

Embody

Low flat-rate compounded GLP-1 pricing at every dose

8.3

Found

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Amazon One Medical vs Trally Meds: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $249/mo for Trally Meds. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 6.8/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Trally Meds is a better fit if you want people who want published GLP-1 prices with free consultations and the option to buy one month at a time.
Amazon One Medical lists availability in 50 states, while Trally Meds's state list is not publicly listed.
Neither Amazon One Medical nor Trally Meds is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

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Continue exploring Amazon One Medical and Trally Meds head-to-heads in the same category.

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