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Amazon One Medical vs SexyMD

In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; SexyMD $199/mo for compounded semaglutide (different medications, so not compared on price)
Coverage
Amazon One Medical 50 states (SexyMD doesn't publish a state list)
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); SexyMD: not stated

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

SexyMD logo

SexyMD

Best for shoppers who want installment financing and can commit to a longer plan

semaglutide

$199/mo

Our score 7.1/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

SexyMD

Price

Semaglutide / month

Not listed

$199/mo

Tirzepatide / month

Not listed

$299/mo

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Coverage

State availability

50 states

List not published

Oral option listed

Yes

Not listed

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Not listed

Included in the price

Clinician visits, shipping

Not included: medication, labs

Not disclosed

Terms & safety

Price shown

Before intake

Before intake

Lab work

Required

Not disclosed

Minimum commitment

Not disclosed

Plans are sold as 4/12/24/48-week terms; the 24- and 48-week plans ship every 12 weeks

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Amazon One Medical · SexyMD

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which SexyMD doesn't price
  • Publishes its full state list (50 states)
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
  • You must provide recent lab results (kidney function and glucose or A1c), bought separately if you have none
SexyMD logo

Choose SexyMD if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • All four commitment tiers are published on the product page with the per-month rate for each, before any intake.
  • The terms name the pharmacy types used — U.S.-licensed 503A pharmacies and 503B outsourcing facilities — instead of leaving it vague.

What to weigh up

  • No published state list; confirm yours at signup
  • The advertised "from $199 per month" is the 48-week commitment; the month-to-month rate is $269, about 35% higher.

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

SexyMD

7.1/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.8A
vs
B
6.5

Accessibility10%

9.5A
vs
B
7.5

Support10%

8.0A
vs
B
6.5

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

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From $247/mo

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7.1

AgelessRx

Longevity-focused GLP-1 care with microdosing and brand-name options

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From $139/mo

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7.2

Willow

Needle-free compounded semaglutide or tirzepatide tablets

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From $299/mo

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Amazon One Medical vs SexyMD: FAQ

Amazon One Medical scores higher overall at 8.5/10 versus 7.1/10, and is particularly strong for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery. That said, SexyMD is a better fit if you want shoppers who want installment financing and can commit to a longer plan.
Neither Amazon One Medical nor SexyMD is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Not at a published price. Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro; SexyMD lists compounded semaglutide, compounded tirzepatide.
Amazon One Medical publishes 50 states. SexyMD doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
Amazon One Medical doesn't state its cancellation terms. SexyMD: cancel anytime — not disclosed; minimum commitment — Plans are sold as 4/12/24/48-week terms; the 24- and 48-week plans ship every 12 weeks; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Amazon One Medical and SexyMD head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.