Amazon One Medical vs RxPros
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
Amazon One Medical and RxPros are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, RxPros starts lower at $99.99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
RxPros
Lowest tier, requires annual prepay; 3-month shipments. All doses same price; includes doctor visit + overnight shipping.
Lowest tier, requires annual prepay; 3-month shipments. All doses same price; includes doctor visit + shipping.
First-month introductory discount for new patients, or paid quarterly. 'Now only $149' banner price also shown.
First-month introductory discount for new patients, or paid quarterly. 'Now only $249' banner price also shown.
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
RxPros
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
RxPros
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | RxPros |
|---|---|---|
| Starting Price | $149/mo | ✓$99.99/mo |
| Features | 6 features | 6 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About RxPros
RxPros (rxpros.com) is a Wyoming-incorporated compounded GLP-1 telehealth platform (RxPros LLC, 1309 Coffeen Ave Ste 15880, Sheridan, WY 82801). LegitScript Certified. Compounded semaglutide $99.99/month and compounded tirzepatide $144.97/month at the introductory + paid-annually tier. Includes the doctor visit, medication, and overnight cold shipping. Add-on options for Zofran (anti-nausea) and B12.
Read our full RxPros review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
RxPros
What we like
- $99.99/month compounded semaglutide — among the cheapest in the US compounded telehealth market
- $144.97/month compounded tirzepatide — at the lower end of the compounded tirzepatide range
- LegitScript Certified
- Named legal entity (RxPros LLC) with a physical Wyoming address
- Overnight cold-packed shipping disclosed — important for GLP-1 cold-chain integrity
- Add-on Zofran (anti-nausea) and B12 available for managing GI side effects during titration
- Flat pricing across all doses ('Same Price for ALL Dosages, no membership or hidden fees'); 3-month supply shipments
Watch-outs
- Per-state availability not listed — verify your state ships before committing
- Specific 503A pharmacy partners not named
- Lab work not included as standard
- LegitScript certification number not displayed (seal only)
- Lowest headline prices ($99.99 sema / $144.97 tirz) require annual prepay; intro-first-month/quarterly tier is $134.99 sema / $224.99 tirz
Our Verdict
Amazon One Medical edges out RxPros with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. RxPros remains a solid alternative, especially if you're looking for lowest annual-prepay compounded GLP-1 monthly rate.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose RxPros if…
You want lowest annual-prepay compounded GLP-1 monthly rate and a starting price around $99.99/mo.
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Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Amazon One Medical vs RxPros: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.