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Amazon One Medical vs Navio MD

In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.5 out of 10), and Amazon One Medical costs less for brand-name Zepbound / Mounjaro (about $1,453 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $299/mo vs Navio MD $445/mo for brand-name Zepbound / Mounjaro (standing prices, no prepay or separate membership listed · about $1,453 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
Both serve the same 50 states
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); Navio MD: medication, shipping

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Zepbound / Mounjaro

$299/mo

billed every 4 weeks

Our score 8.5/10

Navio MD logo

Navio MD

Best for compounded tirzepatide with a brand-name Zepbound option in all 50 states

tirzepatide

$189/mo

Our score 7.5/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

Navio MD

Price

Brand Zepbound / Mounjaro / month

Better on this row: $299/mo

billed every 4 weeks

$445/mo

Brand Zepbound / Mounjaro / year (modeled)

Better on this row: $3,887

13 charges

$5,340

Tirzepatide / month

Not listed

$189/mo

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Coverage

State availability

50 states

50 states

Oral option listed

Yes

Not listed

Brand-name access listed

Zepbound / Mounjaro, Wegovy / Ozempic, Wegovy pill / Rybelsus, Foundayo

Zepbound / Mounjaro

Included in the price

Clinician visits, shipping

Not included: medication, labs

Medication, shipping

FSA/HSA accepted

Not listed

Yes

Terms & safety

Price shown

Before intake

Before intake

Lab work

Required

Not disclosed

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

None stated

Refunds

Not disclosed

No refunds once medication ships; medication refunded if you're not approved, but not the visit fee

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

October 2026

Every dose and plan: Amazon One Medical · Navio MD

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • About $1,453 a year less than Navio MD for brand-name Zepbound / Mounjaro at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Lists brand-name Wegovy / Ozempic, brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which Navio MD doesn't price
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Navio MD logo

Choose Navio MD if…

  • Lists compounded tirzepatide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • Accepts FSA/HSA cards

What to weigh up

  • About $1,453 a year more than Amazon One Medical for brand-name Zepbound / Mounjaro (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Tirzepatide only; no compounded semaglutide and no Ozempic or Wegovy

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Navio MD

7.5/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.8A
vs
B
7.8

Accessibility10%

9.5A
vs
B
7.5

Support10%

8.0A
vs
B
7.9

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Amazon One Medical vs Navio MD: FAQ

For brand-name Zepbound / Mounjaro, Amazon One Medical costs less: about $1,453 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
Amazon One Medical scores higher overall at 8.5/10 versus 7.5/10, and is particularly strong for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery. That said, Navio MD is a better fit if you want compounded tirzepatide with a brand-name Zepbound option in all 50 states.
Neither Amazon One Medical nor Navio MD is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Amazon One Medical: $299 (billed every 4 weeks, 13 charges a year), about $3,887 a year. Navio MD: $445, about $5,340 a year. Amazon One Medical costs about $1,453 less a year at these prices.
Both publish the same list (50 states), so where you live won't decide between them.
Amazon One Medical doesn't state its cancellation terms. Navio MD: cancel anytime — yes; minimum commitment — None stated; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

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Continue exploring Amazon One Medical and Navio MD head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.