Amazon One Medical vs MDExam
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Amazon One Medical and MDExam are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $225/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
MDExam
⛔ MDEXAM PUBLISHES TWO DIFFERENT PRICES FOR THIS SAME PRODUCT. /injectable-semaglutide renders 'Semaglutide Weight Loss Program | Price | $192' with NO billing period stated anywhere, while /medications/injectable-semaglutide renders 'Price | $225' for the identical product. We record $225 because it is the ONLY figure the site ever attaches to a period: 'Our program is priced as low as $225 per month, which includes telemedicine visits, nutrition and exercise coaching, and medication.' Treat $192 as an unlabelled promotional figure until a checkout can be walked — /checkout renders an empty body without a session.
'Injectable Tirzepatide Program | Price | $258'. ⚠ NO BILLING PERIOD IS STATED ON THIS CARD EITHER. It is recorded as monthly on the strength of the site-wide FAQ, which frames the whole program as 'as low as $225 per month ... includes telemedicine visits, nutrition and exercise coaching, and medication' — $258 sits above that floor, consistent with a monthly tirzepatide rate. That is an inference from the program framing, not a quoted period, and it should be re-checked at checkout.
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
MDExam
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
MDExam
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | MDExam |
|---|---|---|
| Starting Price | ✓$149/mo | $225/mo |
| Features | ✓6 features | 2 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About MDExam
Telehealth provider whose GLP-1 program bundles telemedicine visits, nutrition and exercise coaching and the medication into one price — stated as as low as $225 per month for semaglutide and $258 for tirzepatide. Note the site publishes a second, lower figure for semaglutide on a different page without saying what period it covers.
Read our full MDExam review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
MDExam
What we like
- Both semaglutide and tirzepatide available
Watch-outs
- Pricing not publicly disclosed
Our Verdict
Amazon One Medical edges out MDExam with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. MDExam remains a solid alternative, especially if you're looking for mainstream telehealth GLP-1 access.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose MDExam if…
You want mainstream telehealth GLP-1 access and a starting price around $225/mo.
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Get started →Amazon One Medical vs MDExam: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.