Amazon One Medical vs LifeRx.md
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; LifeRx.md $147/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Both serve the same 50 states
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); LifeRx.md: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
LifeRx.md
Best for flat-priced compounded semaglutide that doesn't cost more as your dose rises
semaglutide
$147
Our score 7.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
LifeRx.md
Price
Semaglutide / month
Not listed
$147/mo
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Not disclosed
Required
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None; 'No contracts required' and no membership or subscription fees
Refunds
Not disclosed
No returns or refunds on medication once dispensed or shipped; consultation fees are non-refundable once the visit takes place
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · LifeRx.md
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which LifeRx.md doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
- Brand-name Wegovy, Zepbound and Foundayo prescribed by One Medical clinicians and filled by Amazon Pharmacy
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose LifeRx.md if…
- Lists compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Accepts FSA/HSA cards
What to weigh up
- Compounded semaglutide is not FDA-approved for safety, efficacy or quality
- Compounded tirzepatide is no longer listed; semaglutide is the only GLP-1 shown
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
LifeRx.md
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Amazon One Medical vs LifeRx.md: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
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- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- LifeRx.md vs Vytora Health
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.