Amazon One Medical vs Genesis Health
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Genesis Health
Best for: compounded or brand GLP-1s with coaching, annual pricing from $99/mo
Visit Genesis Health →Amazon One Medical and Genesis Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $175/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Genesis Health
Compounded semaglutide injection. Monthly: $175/mo. Quarterly: $145/mo ($435 billed every 3 months). Bi-Annual: $120/mo ($720 every 6 months). Annual: $99/mo ($1,188/yr). Includes physician consult, medication, and free shipping.
Compounded tirzepatide injection. Monthly: $235/mo. Quarterly: $199/mo ($597 billed every 3 months). Bi-Annual: $175/mo ($1,050 every 6 months). Annual: $125/mo ($1,500/yr). Includes physician consult, medication, and free shipping.
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Genesis Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Genesis Health
7.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Genesis Health |
|---|---|---|
| Starting Price | ✓$149/mo | $175/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | ✓None | 1 warning |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Genesis Health
Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound. Monthly plans start at $175/mo for semaglutide and $235/mo for tirzepatide, with annual plans as low as $99/mo and $125/mo respectively. Every plan includes a free physician consultation, personalized dosing, health coaching, active community access, and free expedited shipping. LegitScript certified; medications sourced from audited US-based compounding pharmacies; FSA/HSA eligible.
Read our full Genesis Health review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Genesis Health
What we like
- Annual plan as low as $99/mo for semaglutide or $125/mo for tirzepatide
- Offers both compounded and brand-name GLP-1s (Wegovy, Ozempic, Zepbound) in one platform
- Includes health coaching, active community, and free expedited shipping on every plan
- LegitScript certified; medications sourced from audited, licensed US compounding pharmacies
- Same-day provider visits, personalized dosing, and 24/7 care team messaging
Watch-outs
- States served not publicly listed; telehealth coverage unconfirmed for all states
- Monthly starting price ($175 sema / $235 tirz) is mid-market without annual commitment
- Labs not disclosed or included in any published plan tier
- Brand-name GLP-1 pricing not published; insurance or coupon required
- Compounded medications are not FDA-approved
Our Verdict
Amazon One Medical edges out Genesis Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Genesis Health remains a solid alternative, especially if you're looking for compounded or brand GLP-1s with coaching, annual pricing from $99/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose Genesis Health if…
You want compounded or brand GLP-1s with coaching, annual pricing from $99/mo and a starting price around $175/mo.
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Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
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Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Amazon One Medical vs Genesis Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.