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Amazon One Medical vs Fierce Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical
VS
Fierce Health logo

Fierce Health

6.9
★★★3.5/5

Best for: compounded GLP-1: standard or microdose dosing, plus longevity add-ons

Visit Fierce Health

Amazon One Medical and Fierce Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $197/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

Fierce Health

Semaglutide Weight Loss Program, monthlyCompounded
$297/mo
semaglutide

Also sold as 3-month and 6-month paid-in-full cadences. Free US shipping.

Tirzepatide Weight Loss Program, monthlyCompounded
$497/mo
tirzepatide

Also sold as 3-month and 6-month paid-in-full cadences.

Semaglutide Microdose Program, monthly (low-dose protocol)Compounded
$197/mo
semaglutide

Listed as "From $197.00"; one vial per month.

Tirzepatide Microdose Program, monthly (low-dose protocol)Compounded
$297/mo
tirzepatide

Listed as "From $297.00"; one vial per month.

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Fierce Health

What the monthly price covers

Medication

Not disclosed

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Fierce Health

6.9/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

8.8A
vs
B
6.0

Accessibility10%

9.5A
vs
B
7.0

Support10%

8.0A
vs
B
7.0

Features & Coverage

FeatureAmazon One MedicalFierce Health
Starting Price$149/mo$197/mo
Features6 features5 features
States Available5030
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNone5 warnings

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About Fierce Health

Fierce Health is a direct-to-consumer telehealth brand selling compounded semaglutide and tirzepatide in both standard and microdose programs, alongside a longevity catalog. Its four-program GLP-1 ladder is broader than peers that sell only one or two SKUs, with a microdose tier among the lower entry points. Pricing runs $197–$497/mo; service is limited to 30 enumerated states, and it's LegitScript Certified.

Read our full Fierce Health review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Fierce Health

What we like

  • 30-state service list spelled out in the Terms — buyers can verify eligibility before intake
  • LegitScript Certified
  • Publishes the FDA compounded-medication disclaimer on every product page
  • Four GLP-1 programs (standard and microdose semaglutide and tirzepatide) — a broader ladder than peers
  • Microdose tier at $197/mo is one of the lower entry points we've seen
  • Explicit refund policy if they can't ship to your state
  • Monthly, 3-month, and 6-month subscription options

Watch-outs

  • No named 503A compounding pharmacy partner — only generic 'partner pharmacies' language
  • Operating LLC name not disclosed anywhere on the site
  • Tirzepatide weight-loss program ($497/mo) showing 'sold out or unavailable' across all plans at review time
  • Clinical provider network not named
  • Sells gray-market longevity products (ivermectin, methylene blue) alongside GLP-1s — an unusual category mix
  • Only LegitScript — no PCAB, BBB, or NABP .pharmacy presence
  • Tirzepatide tier at $497/mo is at the high end of the segment
  • Compounded semaglutide and tirzepatide are not FDA-approved

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Fierce Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Fierce Health remains a solid alternative, especially if you're looking for compounded GLP-1: standard or microdose dosing, plus longevity add-ons.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

Choose Fierce Health if…

You want compounded GLP-1: standard or microdose dosing, plus longevity add-ons and a starting price around $197/mo.

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7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

7.5

PeterMD

Men wanting flat-priced compounded GLP-1 with TRT or peptides

Amazon One Medical vs Fierce Health: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $197/mo for Fierce Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 6.9/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Fierce Health is a better fit if you want compounded GLP-1: standard or microdose dosing, plus longevity add-ons.
Amazon One Medical covers more — 50 states versus 30.
Neither Amazon One Medical nor Fierce Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring Amazon One Medical and Fierce Health head-to-heads in the same category.

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