Amazon One Medical vs Avono Health
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.4 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Avono Health $159/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states (Avono Health doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Avono Health: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Avono Health
Best for No-membership compounded GLP-1 pricing across injection, oral and microdose options
semaglutide
$159
microdose plan
Our score 7.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Avono Health
Price
Semaglutide / month
Not listed
$159/mo
microdose plan
Tirzepatide / month
Not listed
$219/mo
microdose plan
Oral semaglutide / month
Not listed
$219/mo
microdose plan
Oral tirzepatide / month
Not listed
$239/mo
microdose plan
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Minimum commitment
Not disclosed
None stated; monthly or multi-month options on select treatments
Refunds
Not disclosed
Non-refundable once a provider reviews your intake, a prescription is issued or the pharmacy starts processing
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · Avono Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Avono Health doesn't price
- Publishes its full state list (50 states)
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Avono Health if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- No membership fee, no clinician fee and free, discreet shipping
What to weigh up
- No published state list; confirm yours at signup
- Compounded medications are not FDA-approved brand-name products
Amazon One Medical and Avono Health in context
No medication appears on both price lists, so there is no fair price comparison to make. Amazon One Medical lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, while Avono Health lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide. If you have not settled on a medication yet, our Wegovy page and semaglutide page cover what each one is approved for and what it costs. In our scoring, Amazon One Medical is at 8.5 and Avono Health at 7.4 out of 10.
Amazon One Medical prices only brand-name medication, while Avono Health sells compounded versions prepared by a pharmacy. That is a bigger difference than the monthly figure suggests, and our compounded vs brand-name decision guide walks through it. Amazon One Medical publishes where it ships (50 states); Avono Health does not publish a state list, so confirm yours at intake or start from providers by state.
The next head-to-head for Amazon One Medical is Amazon One Medical vs AZ Health; AZ Health sells semaglutide and tirzepatide. For Avono Health, it is Avono Health vs Vytora Health; Vytora Health sells semaglutide and tirzepatide and lists 50 states + DC. If neither fits, the wider shortlists are alternatives to Amazon One Medical and alternatives to Avono Health.
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Avono Health
7.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $79/mo (sale price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →Found
Medication-included compounded GLP-1 from $169/mo on a 12-month prepaid plan, plus brand insurance help
Read full review →From $289/4 wks (billed per 4 weeks)
Get started →Amazon One Medical vs Avono Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and Avono Health head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- Avono Health vs Vytora Health
Or see the full category ranking, or alternatives to Amazon One Medical and Avono Health.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.