1st Optimal vs Revel Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Revel Health
Best for: GLP-1 weight loss bundled with NAD+, sermorelin and longevity care
Visit Revel Health →1st Optimal and Revel Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $199/mo, and Revel Health edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Revel Health
'Semaglutide Injection — From $199/mo — First month $99.' Revel states 'One price, everything included — consultation, medication, supplies, and shipping.'
'Tirzepatide Injection — From $249/mo — First month $149', on the same all-in terms.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Revel Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Revel Health
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Revel Health |
|---|---|---|
| Starting Price | ✓$99/mo | $199/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 45 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Revel Health
Revel Health is a telehealth platform combining GLP-1 weight loss with longevity care — semaglutide and tirzepatide plus NAD+, sermorelin and peptide therapy — prescribed by board-certified physicians and compounded in USP 795/800-compliant facilities. You complete an online intake, a physician reviews it within the hour, and medication ships to you. It's LegitScript certified and serves 45 states (not AK, AR, NC, NJ or MS). Published pricing isn't shown upfront.
Read our full Revel Health review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Revel Health
What we like
- LegitScript certified with board-certified physicians and USP 795/800 compounding
- Combines GLP-1 weight loss with NAD+, sermorelin and longevity care
- Fast intake — a physician reviews within the hour
- Available in 45 states with a clear list of where it operates
Watch-outs
- Doesn't show upfront pricing — you learn cost during checkout
- Not available in AK, AR, NC, NJ or MS
- Compounded medications only — no brand-name options noted
- Longevity add-ons add cost beyond the core GLP-1 program
Our Verdict
Revel Health edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for GLP-1 weight loss bundled with NAD+, sermorelin and longevity care. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Revel Health if…
You want GLP-1 weight loss bundled with NAD+, sermorelin and longevity care and a starting price around $199/mo.
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Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →1st Optimal vs Revel Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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