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1st Optimal vs Revel Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Revel Health logo

Revel Health

7.1
★★★3.6/5

Best for: people wanting GLP-1 weight loss bundled with NAD+, sermorelin and longevity care

Visit Revel Health

1st Optimal and Revel Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Revel Health starts at $199/mo, and Revel Health edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

Revel Health

Compounded program (preliminary)compounded injection
$199/mo
semaglutide

Preliminary placeholder — Revel doesn't show upfront pricing; confirm at checkout

StartingCompounded
$249/mo
tirzepatide

Tirzepatide injection from $249/mo (first month $149)

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What’s included

1st Optimal

Inclusions not disclosed.

Revel Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Revel Health

7.1/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.5

Trust & Safety15%

6.5A
vs
B
7.8

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalRevel Health
Starting Price$199/mo
Features8 features8 features
States AvailableNot disclosed45
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Revel Health

Revel Health is a telehealth platform combining GLP-1 weight loss with longevity care — semaglutide and tirzepatide plus NAD+, sermorelin and peptide therapy — prescribed by board-certified physicians and compounded in USP 795/800-compliant facilities. You complete an online intake, a physician reviews it within the hour, and medication ships to you. It's LegitScript certified and serves 45 states (not AK, AR, NC, NJ or MS). Published pricing isn't shown upfront.

Read our full Revel Health review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Revel Health

What we like

  • LegitScript certified with board-certified physicians and USP 795/800 compounding
  • Combines GLP-1 weight loss with NAD+, sermorelin and longevity care
  • Fast intake — a physician reviews within the hour
  • Available in 45 states with a clear list of where it operates

Watch-outs

  • Doesn't show upfront pricing — you learn cost during checkout
  • Not available in AK, AR, NC, NJ or MS
  • Compounded medications only — no brand-name options noted
  • Longevity add-ons add cost beyond the core GLP-1 program

Our Verdict

Winner: Revel Health

Revel Health edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for people wanting GLP-1 weight loss bundled with NAD+, sermorelin and longevity care. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose Revel Health if…

You want people wanting GLP-1 weight loss bundled with NAD+, sermorelin and longevity care and a starting price around $199/mo.

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7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

8.1

GobyMeds

Budget-conscious shoppers

6.4

Direct Meds

Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering

1st Optimal vs Revel Health: FAQ

Key terms, explained

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