1st Optimal vs Options Medical Weight Loss
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Options Medical Weight Loss
Best for: people wanting a structured medical weight-loss program with compounded GLP-1 and provider accountability
Visit Options Medical Weight Loss →1st Optimal and Options Medical Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Options Medical Weight Loss starts at $239/mo, and Options Medical Weight Loss edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Options Medical Weight Loss
Compounded; programs start at $199/mo, HSA/FSA eligible
Compounded; higher tiers $339-$399/mo
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 400+ providers' prices on their own sites and email you when tracked prices move.
What’s included
1st Optimal
Inclusions not disclosed.
Options Medical Weight Loss
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Options Medical Weight Loss
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Options Medical Weight Loss |
|---|---|---|
| Starting Price | — | $239/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Options Medical Weight Loss
Options Medical Weight Loss offers telehealth medical weight-loss programs built around compounded GLP-1 — semaglutide starting around $239/month and tirzepatide from $299/month, plus NAD+ injections at $199/month. GLP-1 is used as one tool within a broader metabolic-health plan with provider support and accountability; programs start at $199/month and are HSA/FSA eligible. It is LegitScript certified, and the brand also runs in-person clinics alongside its online program.
Read our full Options Medical Weight Loss review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Options Medical Weight Loss
What we like
- LegitScript certified with clear, upfront program pricing
- Compounded semaglutide (~$239) and tirzepatide (from $299), plus NAD+
- Structured metabolic-health program with provider support and accountability
- HSA/FSA eligible with flexible payment options
Watch-outs
- Doesn't clearly publish which states its telehealth covers
- Tirzepatide tiers climb to $339-$399/month
- More program structure (and cost) than medication-only sellers
- Compounded GLP-1 only online — no brand-name options noted
Our Verdict
Options Medical Weight Loss edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for people wanting a structured medical weight-loss program with compounded GLP-1 and provider accountability. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose Options Medical Weight Loss if…
You want people wanting a structured medical weight-loss program with compounded GLP-1 and provider accountability and a starting price around $239/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →1st Optimal vs Options Medical Weight Loss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 1st Optimal and Options Medical Weight Loss head-to-heads in the same category.
- 1st Optimal vs Amazon One Medical
- 1st Optimal vs Vytora Health
- 1st Optimal vs CoreAge Rx
- Options Medical Weight Loss vs EverSlim
- Options Medical Weight Loss vs Found
- Options Medical Weight Loss vs NewSelf
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.