1st Optimal vs Kongo
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programKongo
Best for Low-cost compounded semaglutide or tirzepatide nationwide with no membership and everything includedStarting at $119/mo
Side-by-Side Comparison
| Feature | 1st Optimal | Kongo |
|---|---|---|
| Overall Score | 6.7/10 | ✓8.4/10 |
| Starting Price | — | $119/mo |
| Editorial Rating | 3.4 ★ /5 | ✓4.2 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Kongo
What we like
- Among the lowest compounded GLP-1 prices: semaglutide $119/month and tirzepatide $229/month
- Available in all 50 states with no membership fee, and provider, supplies, and free shipping always included
- Verifiable LegitScript certification (seal ID 45229340)
- Fast and simple: 4-minute intake with no video call and provider approval within 24 hours
- Also offers longevity treatments (NAD+, sermorelin, glutathione) if you want more than GLP-1
Watch-outs
- Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- The compounding pharmacy is described only as a 'licensed US pharmacy' and not named
- Newer brand; member testimonials are the main social proof
- Some verticals (Longevity, Intimacy) are still listed as 'coming soon'
Our Verdict
Kongo edges out 1st Optimal with a higher overall score of 8.4/10 and is particularly strong for Low-cost compounded semaglutide or tirzepatide nationwide with no membership and everything included. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.