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10rx vs Trillium Meds

An in-depth comparison of two leading GLP-1 Providers

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10rx logo

10rx

7.0
★★★3.5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

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VS
Trillium Meds logo

Trillium Meds

7.2
★★★3.6

Best for: LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo)

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10rx and Trillium Meds are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $119/mo, and Trillium Meds edges ahead overall (7.2 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Trillium Meds

3-Month PlanCompounded
$119/mo
semaglutide

Verbatim site meta: 'pricing from $109.' 3-month plan at $119/mo ($357 total); 1-month plan at $159/mo. All-inclusive price covers compounded semaglutide (with B6, dispensed by BPI Labs or ProRx pharmacy), provider consultation, and shipping. No additional fees.

3-Month PlanCompounded
$199/mo
tirzepatide

3-month plan at $199/mo ($599 total); 1-month plan at $249/mo. All-inclusive price covers compounded tirzepatide (with B6, dispensed by BPI Labs or ProRx pharmacy), provider consultation, and shipping. No additional fees.

What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Trillium Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Billed separately

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.0/10

Overall

Trillium Meds

7.2/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
6.0

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

5.0A
vs
B
7.5

Accessibility10%

7.5A
vs
B
9.5

Support10%

6.0A
vs
B
7.0

Features & Coverage

Feature10rxTrillium Meds
Starting Price$99.67/mo$119/mo
Features8 features8 features
States AvailableNot disclosed52
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Trillium Meds

Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded semaglutide and tirzepatide. Pricing is all-inclusive—covering medication, provider consultation, and shipping—with no membership fees and flexible 1-month, 3-month fixed-dose, or 3-month titrated programs. LegitScript certified and available in all 50 states plus Puerto Rico.

Read our full Trillium Meds review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Trillium Meds

What we like

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Watch-outs

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Our Verdict

Winner: Trillium Meds

Trillium Meds edges out 10rx with a higher overall score of 7.2/10 and is particularly strong for LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Trillium Meds if…

You want LegitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo) and a starting price around $119/mo.

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Lowest first-month entry pricing on compounded GLP-1s

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TrimRx

Best overall value

8.2

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Needle-free and microdosed compounded GLP-1 options with lab-monitored care

10rx vs Trillium Meds: FAQ

Key terms, explained

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