10rx vs TMates
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
TMates
Best for nationwide compounded GLP-1 availability including Puerto RicoStarting at $249/mo
Side-by-Side Comparison
| Feature | 10rx | TMates |
|---|---|---|
| Overall Score | ✓7.0/10 | 6.3/10 |
| Starting Price | ✓$99.67/mo | $249/mo |
| Editorial Rating | ✓3.5 ★ /5 | 3.2 ★ /5 |
| Features | ✓8 features | 4 features |
| States Available | 0 | ✓50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
TMates
What we like
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
- Available in all 50 states plus Puerto Rico and other US territories
- Both compounded semaglutide and tirzepatide offered
- Fast stated turnaround — 2–3 days from intake to delivery
Watch-outs
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
- BBB rating of B+ (not accredited) with complaints centered on billing and cancellation
- Trustpilot reports of partial refunds and difficulty reaching support
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Pharmacy partners not named; routes medical and dispensing to third parties
- Also sells testosterone and other wellness products — not GLP-1-focused
- Lowest per-month prices require prepaying for 6- or 12-month plans ($1,050-$1,999 upfront)
Our Verdict
10rx edges out TMates with a higher overall score of 7.0/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. TMates remains a solid alternative, especially if you're looking for nationwide compounded GLP-1 availability including Puerto Rico.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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