10rx vs Prime Doctor RX
An in-depth comparison of two leading GLP-1 Providers
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Prime Doctor RX
Best for: month-to-month compounded GLP-1s with every prepaid tier priced up front, plus TRT
Visit Prime Doctor RX →10rx and Prime Doctor RX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $249/mo, and 10rx edges ahead overall (7.1 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Prime Doctor RX
'Month-to-month: $249 every 4 weeks'. Prepaid: '12 weeks upfront $657 · $219/mo', '24 weeks upfront $1,194 · $199/mo', '52 weeks upfront $2,327 · $179/mo' (each /mo figure is per 4 weeks).
'Month-to-month: $339 every 4 weeks'. Prepaid: '12 weeks upfront $927 · $309/mo', '24 weeks upfront $1,734 · $289/mo', '52 weeks upfront $3,497 · $269/mo' (each /mo figure is per 4 weeks).
'Month-to-month: $279 every 4 weeks'. Prepaid: '12 weeks upfront $777 · $259/mo', '24 weeks upfront $1,434 · $239/mo', '52 weeks upfront $2,717 · $209/mo' (each /mo figure is per 4 weeks).
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Prime Doctor RX
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Prime Doctor RX
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Prime Doctor RX |
|---|---|---|
| Starting Price | ✓$96.67/mo | $249/mo |
| Features | ✓8 features | 7 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Prime Doctor RX
Prime Doctor RX is a telehealth brand selling compounded semaglutide injections, tirzepatide injections and an oral semaglutide tablet, with care provided by the medical group OpenLoop Healthcare Partners, PC. Month-to-month plans cost $249, $339 and $279, charged every 4 weeks, and every longer prepaid option is priced on the homepage before you start. It also runs testosterone and enclomiphene programs for men.
Read our full Prime Doctor RX review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Prime Doctor RX
What we like
- Every plan is priced on the homepage before you start, with month-to-month and 12-, 24- and 52-week prepaid rates for each drug
- Names its prescribing medical group, OpenLoop Healthcare Partners, PC
- Offers compounded semaglutide and tirzepatide injections plus a daily oral semaglutide tablet
- States the real billing cycle plainly: month-to-month plans are charged every 4 weeks
- Month-to-month plans can be canceled at any time, and refunds can be requested for unused future periods
- Also runs testosterone and enclomiphene programs for eligible men, with the hormone-care state list published
Watch-outs
- The '$179/mo' headline is the 52-week prepay average, paid as one $2,327 charge; month-to-month semaglutide is $249
- Plans are charged every 4 weeks, so month-to-month billing comes to 13 charges a year, not 12
- Ending a prepaid plan early can reprice the months you used at the higher month-to-month rate
- No dispensing pharmacy is named anywhere on the site
- No LegitScript certification, and no Trustpilot profile or other third-party reviews could be found
- Weight-loss availability by state is not published; it is confirmed during intake
- No phone number is published on the site; support is by email and an on-site chat widget
- Product cards never say compounded or brand-name; only a footnote says compounded medications are not FDA-approved
Our Verdict
10rx edges out Prime Doctor RX with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Prime Doctor RX remains a solid alternative, especially if you're looking for month-to-month compounded GLP-1s with every prepaid tier priced up front, plus TRT.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose Prime Doctor RX if…
You want month-to-month compounded GLP-1s with every prepaid tier priced up front, plus TRT and a starting price around $249/mo.
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Synergy Rx
Broadest drug catalog in the Lion MD white-label cluster
From $199/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →10rx vs Prime Doctor RX: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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