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10rx vs PCOS Sisters

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS

PCOS Sisters

7.2
★★★3.6/5

Best for: women with pcos seeking glp-1 weight and metabolic care

Visit PCOS Sisters

10rx and PCOS Sisters are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $150/mo, and PCOS Sisters edges ahead overall (7.2 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

PCOS Sisters

All doses (flat)Compounded
$150/mo
semaglutide

GLP-1 management fee, membership required; billed monthly

All doses (flat)Compounded
$150/mo
tirzepatide

Same 150/mo GLP-1 management fee; tirzepatide referenced in program

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

PCOS Sisters

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

PCOS Sisters

7.2/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

5.3A
vs
B
7.0

Accessibility10%

7.5A
vs
B
6.5

Support10%

6.4A
vs
B
7.0

Features & Coverage

Feature10rxPCOS Sisters
Starting Price$99.67/mo$150/mo
Features8 features6 features
States AvailableNot disclosed12
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About PCOS Sisters

PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. Providers prescribe semaglutide (the active ingredient in Wegovy and Ozempic), tirzepatide, and oral GLP-1 options, integrated with a PCOS-focused metabolic program and fitness app. Care is available across 12 states and prescriptions are filled through named partner pharmacies including Strive Pharmacy and Striker Pharmacy. Cash-pay model, no insurance.

Read our full PCOS Sisters review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

PCOS Sisters

What we like

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Watch-outs

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Our Verdict

Winner: PCOS Sisters

PCOS Sisters edges out 10rx with a higher overall score of 7.2/10 and is particularly strong for women with pcos seeking glp-1 weight and metabolic care. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose PCOS Sisters if…

You want women with pcos seeking glp-1 weight and metabolic care and a starting price around $150/mo.

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10rx vs PCOS Sisters: FAQ

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