10rx vs Open Water Rx
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Open Water Rx
Best for transparency listing only — verify against vetted providers firstSide-by-Side Comparison
| Feature | 10rx | Open Water Rx |
|---|---|---|
| Overall Score | ✓7.0/10 | 4.9/10 |
| Starting Price | $99.67/mo | — |
| Editorial Rating | ✓3.5 ★ /5 | 2.5 ★ /5 |
| Features | ✓8 features | 0 features |
| States Available | 0 | 0 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Open Water Rx
What we like
- Combines weight-loss and longevity verticals in one brand
- Established brand domain
Watch-outs
- Limited public data — most details are gated behind signup or rendered only in JavaScript
- Pricing not disclosed
- GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
- States-served list not disclosed
- Pharmacy partner not named
- LegitScript certification not confirmed
- No FDA compounded-medication disclaimer found
- Named medical director not disclosed
Our Verdict
10rx edges out Open Water Rx with a higher overall score of 7.0/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Open Water Rx remains a solid alternative, especially if you're looking for transparency listing only — verify against vetted providers first.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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