10rx vs Open Water Rx
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Open Water Rx
Best for: transparency listing only — verify against vetted providers first
Visit Open Water Rx →10rx and Open Water Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts at $99.67/mo, and 10rx edges ahead overall (7.1 vs 4.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Open Water Rx
Pricing not publicly listed.
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Open Water Rx
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Open Water Rx
4.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Open Water Rx |
|---|---|---|
| Starting Price | $99.67/mo | — |
| Features | ✓8 features | 0 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Open Water Rx
Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site. Most details — medications, pricing, states served, pharmacy partner, and clinical leadership — are not surfaced publicly, so this entry exists mainly to confirm the brand and category. Verify specifics directly with the provider before enrolling.
Read our full Open Water Rx review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Open Water Rx
What we like
- Combines weight-loss and longevity verticals in one brand
- Established brand domain
Watch-outs
- Limited public data — most details are gated behind signup or rendered only in JavaScript
- Pricing not disclosed
- GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
- States-served list not disclosed
- Pharmacy partner not named
- LegitScript certification not confirmed
- No FDA compounded-medication disclaimer found
- Named medical director not disclosed
Our Verdict
10rx edges out Open Water Rx with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Open Water Rx remains a solid alternative, especially if you're looking for transparency listing only — verify against vetted providers first.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Open Water Rx if…
You want transparency listing only — verify against vetted providers first.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →10rx vs Open Water Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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